Close encounters of the lysosome-peroxisome kind.

Jin, Yui; Strunk, Bethany S; Weisman, Lois S

Jin, Yui; Strunk, Bethany S; Weisman, Lois S.

Afiliación

Jin Y; Department of Cell and Developmental Biology, Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
Strunk BS; Department of Cell and Developmental Biology, Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
Weisman LS; Department of Cell and Developmental Biology, Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA. Electronic address: lweisman@umich.edu.

Cell ; 161(2): 197-8, 2015 Apr 09.

Article en En | MEDLINE | ID: mdl-25860602

RESUMEN

Lysosomes provide a major source for cellular cholesterol; however, most of this cholesterol is trafficked to the plasma membrane via unknown mechanisms. Chu et al. identify an unexpected role for peroxisomes in the transport of cholesterol from the lysosome to the plasma membrane via a lysosome-peroxisome membrane contact site.

Asunto(s)

Colesterol/metabolismo; Lisosomas/metabolismo; Peroxisomas/metabolismo; ARN Interferente Pequeño/metabolismo; Animales; Humanos

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Colesterol / Peroxisomas / ARN Interferente Pequeño / Lisosomas Límite: Animals / Humans Idioma: En Revista: Cell Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos

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