Genetic analyses of GII.17 norovirus strains in diarrheal disease outbreaks from December 2014 to March 2015 in Japan reveal a novel polymerase sequence and amino acid substitutions in the capsid region.
Euro Surveill
; 20(26)2015 Jul 02.
Article
en En
| MEDLINE
| ID: mdl-26159307
ABSTRACT
A novel GII.P17-GII.17 variant norovirus emerged as a major cause of norovirus outbreaks from December 2014 to March 2015 in Japan. Named Hu/GII/JP/2014/GII.P17-GII.17, this variant has a newly identified GII.P17 type RNA-dependent RNA polymerase, while the capsid sequence displays amino acid substitutions around histo-blood group antigen (HBGA) binding sites. Several variants caused by mutations in the capsid region have previously been observed in the GII.4 genotype. Monitoring the GII.17 variant's geographical spread and evolution is important.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Brotes de Enfermedades
/
Infecciones por Caliciviridae
/
Sustitución de Aminoácidos
/
Norovirus
/
Disentería
Límite:
Humans
País/Región como asunto:
Asia
Idioma:
En
Revista:
Euro Surveill
Asunto de la revista:
DOENCAS TRANSMISSIVEIS
Año:
2015
Tipo del documento:
Article
País de afiliación:
Japón