Disruption of the Rag-Ragulator Complex by c17orf59 Inhibits mTORC1.

Schweitzer, Lawrence D; Comb, William C; Bar-Peled, Liron; Sabatini, David M

Schweitzer, Lawrence D; Comb, William C; Bar-Peled, Liron; Sabatini, David M.

Afiliación

Schweitzer LD; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA; Department of Biology, MIT, Cambridge, MA 02139, USA; Howard Hughes Medical Institute, MIT, Cambridge, MA 02139, USA; Broad Institute, Cambridge, MA 02142, USA; The David H. Koch Institute for Integrative Cancer Research at MIT,
Comb WC; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA; Department of Biology, MIT, Cambridge, MA 02139, USA; Howard Hughes Medical Institute, MIT, Cambridge, MA 02139, USA; Broad Institute, Cambridge, MA 02142, USA; The David H. Koch Institute for Integrative Cancer Research at MIT,
Bar-Peled L; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA; Department of Biology, MIT, Cambridge, MA 02139, USA; Howard Hughes Medical Institute, MIT, Cambridge, MA 02139, USA; Broad Institute, Cambridge, MA 02142, USA; The David H. Koch Institute for Integrative Cancer Research at MIT,
Sabatini DM; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA; Department of Biology, MIT, Cambridge, MA 02139, USA; Howard Hughes Medical Institute, MIT, Cambridge, MA 02139, USA; Broad Institute, Cambridge, MA 02142, USA; The David H. Koch Institute for Integrative Cancer Research at MIT,

Cell Rep ; 12(9): 1445-55, 2015 Sep 01.

Article en En | MEDLINE | ID: mdl-26299971

Asunto(s)

Proteínas Adaptadoras Transductoras de Señales/metabolismo; Lisosomas/metabolismo; Proteínas de Unión al GTP Monoméricas/metabolismo; Complejos Multiproteicos/metabolismo; Serina-Treonina Quinasas TOR/metabolismo; Proteínas Adaptadoras Transductoras de Señales/genética; Células HEK293; Células HeLa; Humanos; Diana Mecanicista del Complejo 1 de la Rapamicina; Proteínas de Unión al GTP Monoméricas/genética; Unión Proteica

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas de Unión al GTP Monoméricas / Complejos Multiproteicos / Proteínas Adaptadoras Transductoras de Señales / Serina-Treonina Quinasas TOR / Lisosomas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Cell Rep Año: 2015 Tipo del documento: Article

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