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Discovery of the Aryl-phospho-indole IDX899, a Highly Potent Anti-HIV Non-nucleoside Reverse Transcriptase Inhibitor.
Dousson, Cyril; Alexandre, François-René; Amador, Agnès; Bonaric, Séverine; Bot, Stéphanie; Caillet, Catherine; Convard, Thierry; da Costa, Daniel; Lioure, Marie-Pierre; Roland, Arlène; Rosinovsky, Elodie; Maldonado, Sébastien; Parsy, Christophe; Trochet, Christophe; Storer, Richard; Stewart, Alistair; Wang, Jingyang; Mayes, Benjamin A; Musiu, Chiara; Poddesu, Barbara; Vargiu, Luana; Liuzzi, Michel; Moussa, Adel; Jakubik, Jocelyn; Hubbard, Luke; Seifer, Maria; Standring, David.
Afiliación
  • Dousson C; IDENIX, an MSD Company , 1682 rue de la Valsière, Cap Gamma, BP 50001, 34189 Cedex 4 Montpellier, France.
  • Alexandre FR; IDENIX, an MSD Company , 1682 rue de la Valsière, Cap Gamma, BP 50001, 34189 Cedex 4 Montpellier, France.
  • Amador A; IDENIX, an MSD Company , 1682 rue de la Valsière, Cap Gamma, BP 50001, 34189 Cedex 4 Montpellier, France.
  • Bonaric S; IDENIX, an MSD Company , 1682 rue de la Valsière, Cap Gamma, BP 50001, 34189 Cedex 4 Montpellier, France.
  • Bot S; IDENIX, an MSD Company , 1682 rue de la Valsière, Cap Gamma, BP 50001, 34189 Cedex 4 Montpellier, France.
  • Caillet C; IDENIX, an MSD Company , 1682 rue de la Valsière, Cap Gamma, BP 50001, 34189 Cedex 4 Montpellier, France.
  • Convard T; IDENIX, an MSD Company , 1682 rue de la Valsière, Cap Gamma, BP 50001, 34189 Cedex 4 Montpellier, France.
  • da Costa D; IDENIX, an MSD Company , 1682 rue de la Valsière, Cap Gamma, BP 50001, 34189 Cedex 4 Montpellier, France.
  • Lioure MP; IDENIX, an MSD Company , 1682 rue de la Valsière, Cap Gamma, BP 50001, 34189 Cedex 4 Montpellier, France.
  • Roland A; IDENIX, an MSD Company , 1682 rue de la Valsière, Cap Gamma, BP 50001, 34189 Cedex 4 Montpellier, France.
  • Rosinovsky E; IDENIX, an MSD Company , 1682 rue de la Valsière, Cap Gamma, BP 50001, 34189 Cedex 4 Montpellier, France.
  • Maldonado S; IDENIX, an MSD Company , 1682 rue de la Valsière, Cap Gamma, BP 50001, 34189 Cedex 4 Montpellier, France.
  • Parsy C; IDENIX, an MSD Company , 1682 rue de la Valsière, Cap Gamma, BP 50001, 34189 Cedex 4 Montpellier, France.
  • Trochet C; IDENIX, an MSD Company , 1682 rue de la Valsière, Cap Gamma, BP 50001, 34189 Cedex 4 Montpellier, France.
  • Storer R; IDENIX, an MSD Company , 1682 rue de la Valsière, Cap Gamma, BP 50001, 34189 Cedex 4 Montpellier, France.
  • Stewart A; IDENIX , 320 Bent Street, 4th Floor, Cambridge, Massachusetts 02139, United States.
  • Wang J; IDENIX , 320 Bent Street, 4th Floor, Cambridge, Massachusetts 02139, United States.
  • Mayes BA; IDENIX , 320 Bent Street, 4th Floor, Cambridge, Massachusetts 02139, United States.
  • Musiu C; IDENIX , 320 Bent Street, 4th Floor, Cambridge, Massachusetts 02139, United States.
  • Poddesu B; IDENIX , 320 Bent Street, 4th Floor, Cambridge, Massachusetts 02139, United States.
  • Vargiu L; IDENIX , 320 Bent Street, 4th Floor, Cambridge, Massachusetts 02139, United States.
  • Liuzzi M; IDENIX , 320 Bent Street, 4th Floor, Cambridge, Massachusetts 02139, United States.
  • Moussa A; IDENIX , 320 Bent Street, 4th Floor, Cambridge, Massachusetts 02139, United States.
  • Jakubik J; IDENIX , 320 Bent Street, 4th Floor, Cambridge, Massachusetts 02139, United States.
  • Hubbard L; IDENIX , 320 Bent Street, 4th Floor, Cambridge, Massachusetts 02139, United States.
  • Seifer M; IDENIX , 320 Bent Street, 4th Floor, Cambridge, Massachusetts 02139, United States.
  • Standring D; IDENIX , 320 Bent Street, 4th Floor, Cambridge, Massachusetts 02139, United States.
J Med Chem ; 59(5): 1891-8, 2016 Mar 10.
Article en En | MEDLINE | ID: mdl-26804933
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ácidos Fosfínicos / VIH-1 / Inhibidores de la Transcriptasa Inversa / Fármacos Anti-VIH / Transcriptasa Inversa del VIH / Descubrimiento de Drogas / Indoles Límite: Animals / Humans / Male Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2016 Tipo del documento: Article País de afiliación: Francia
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ácidos Fosfínicos / VIH-1 / Inhibidores de la Transcriptasa Inversa / Fármacos Anti-VIH / Transcriptasa Inversa del VIH / Descubrimiento de Drogas / Indoles Límite: Animals / Humans / Male Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2016 Tipo del documento: Article País de afiliación: Francia