Icaritin suppresses development of neuroendocrine differentiation of prostate cancer through inhibition of IL-6/STAT3 and Aurora kinase A pathways in TRAMP mice.

Sun, Feng; Zhang, Zhi Wei; Tan, Ee Min; Lim, Z L Ryan; Li, Yu; Wang, Xiao Chong; Chua, Seok Eng; Li, Jun; Cheung, Edwin; Yong, Eu-Leong

Sun, Feng; Zhang, Zhi Wei; Tan, Ee Min; Lim, Z L Ryan; Li, Yu; Wang, Xiao Chong; Chua, Seok Eng; Li, Jun; Cheung, Edwin; Yong, Eu-Leong.

Afiliación

Sun F; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Tower Block, Level 12, 1E, Kent Ridge Road, Singapore 119704 and.
Zhang ZW; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Tower Block, Level 12, 1E, Kent Ridge Road, Singapore 119704 and.
Tan EM; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Tower Block, Level 12, 1E, Kent Ridge Road, Singapore 119704 and.
Lim ZLR; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Tower Block, Level 12, 1E, Kent Ridge Road, Singapore 119704 and.
Li Y; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Tower Block, Level 12, 1E, Kent Ridge Road, Singapore 119704 and.
Wang XC; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Tower Block, Level 12, 1E, Kent Ridge Road, Singapore 119704 and.
Chua SE; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Tower Block, Level 12, 1E, Kent Ridge Road, Singapore 119704 and.
Li J; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Tower Block, Level 12, 1E, Kent Ridge Road, Singapore 119704 and.
Cheung E; Faculty of Health Sciences, University of Macau, Macau, China.
Yong EL; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Tower Block, Level 12, 1E, Kent Ridge Road, Singapore 119704 and.

Carcinogenesis ; 37(7): 701-711, 2016 07.

Article en En | MEDLINE | ID: mdl-27207661

Asunto(s)

Aurora Quinasa A/biosíntesis; Carcinoma Neuroendocrino/tratamiento farmacológico; Flavonoides/administración & dosificación; Interleucina-6/biosíntesis; Neoplasias de la Próstata/tratamiento farmacológico; Factor de Transcripción STAT3/biosíntesis; Animales; Aurora Quinasa A/genética; Carcinoma Neuroendocrino/genética; Carcinoma Neuroendocrino/patología; Diferenciación Celular/efectos de los fármacos; Regulación Neoplásica de la Expresión Génica/efectos de los fármacos; Humanos; Interleucina-6/genética; Masculino; Ratones; Ratones Transgénicos; Neoplasias de la Próstata/genética; Neoplasias de la Próstata/patología; Receptores Androgénicos/biosíntesis; Receptores Androgénicos/genética; Factor de Transcripción STAT3/genética; Transducción de Señal; Sinaptofisina/biosíntesis; Sinaptofisina/genética; Microambiente Tumoral/efectos de los fármacos

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Flavonoides / Interleucina-6 / Carcinoma Neuroendocrino / Factor de Transcripción STAT3 / Aurora Quinasa A Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Carcinogenesis Año: 2016 Tipo del documento: Article

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