Extracellular Matrix for Vocal Fold Lamina Propria Replacement: A Review.
Tissue Eng Part B Rev
; 22(6): 421-429, 2016 12.
Article
en En
| MEDLINE
| ID: mdl-27316784
ABSTRACT
The vocal folds (VFs) are exposed to a number of injurious stimuli that frequently lead to aberrant structural alterations and altered biomechanical properties that clinically manifest as voice disorders. Therapies to restore both structure and function of this delicate tissue are ideal. However, such methods have not been adequately developed. Our group and others hypothesize that tissue engineering and regenerative medicine approaches, previously described for other tissue systems, hold significant promise for the VFs. In this review, we explore the concept of tissue engineering as it relates to the VFs, as well as recent studies employing both naturally and synthetically derived biomaterials, including those from laryngeal and nonlaryngeal sources, in combination with stem cells for a tissue-engineered approach to VF repair.
Palabras clave
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Pliegues Vocales
Límite:
Humans
Idioma:
En
Revista:
Tissue Eng Part B Rev
Asunto de la revista:
BIOTECNOLOGIA
/
HISTOLOGIA
Año:
2016
Tipo del documento:
Article