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In vitro hepatotoxicity of 'Legal X': the combination of 1-benzylpiperazine (BZP) and 1-(m-trifluoromethylphenyl)piperazine (TFMPP) triggers oxidative stress, mitochondrial impairment and apoptosis.
Dias da Silva, Diana; Silva, Maria João; Moreira, Patrícia; Martins, Maria João; Valente, Maria João; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena.
Afiliación
  • Dias da Silva D; UCIBIO, REQUIMTE, Laboratory of Toxicology, Departament of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal. diana.dds@gmail.com.
  • Silva MJ; UCIBIO, REQUIMTE, Laboratory of Toxicology, Departament of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal.
  • Moreira P; UCIBIO, REQUIMTE, Laboratory of Toxicology, Departament of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal.
  • Martins MJ; UCIBIO, REQUIMTE, Laboratory of Toxicology, Departament of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal.
  • Valente MJ; UCIBIO, REQUIMTE, Laboratory of Toxicology, Departament of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal.
  • Carvalho F; UCIBIO, REQUIMTE, Laboratory of Toxicology, Departament of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal.
  • Bastos ML; UCIBIO, REQUIMTE, Laboratory of Toxicology, Departament of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal.
  • Carmo H; UCIBIO, REQUIMTE, Laboratory of Toxicology, Departament of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal. helenacarmo@ff.up.pt.
Arch Toxicol ; 91(3): 1413-1430, 2017 Mar.
Article en En | MEDLINE | ID: mdl-27358233
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piperazinas / Estrés Oxidativo / Hepatocitos / Mitocondrias Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Arch Toxicol Año: 2017 Tipo del documento: Article País de afiliación: Portugal
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piperazinas / Estrés Oxidativo / Hepatocitos / Mitocondrias Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Arch Toxicol Año: 2017 Tipo del documento: Article País de afiliación: Portugal