Role of bone marrow macrophages in controlling homeostasis and repair in bone and bone marrow niches.

Kaur, Simranpreet; Raggatt, Liza Jane; Batoon, Lena; Hume, David Arthur; Levesque, Jean-Pierre; Pettit, Allison Robyn

Kaur, Simranpreet; Raggatt, Liza Jane; Batoon, Lena; Hume, David Arthur; Levesque, Jean-Pierre; Pettit, Allison Robyn.

Afiliación

Kaur S; Blood and Bone Diseases Program, Mater Research Institute - The University of Queensland, Faculty of Medicine and Biomedical Sciences, Translational Research Institute, 37 Kent Street, Woolloongabba, 4102, Australia. Electronic address: simranpreet.Kaur@mater.uq.edu.au.
Raggatt LJ; Blood and Bone Diseases Program, Mater Research Institute - The University of Queensland, Faculty of Medicine and Biomedical Sciences, Translational Research Institute, 37 Kent Street, Woolloongabba, 4102, Australia. Electronic address: liza-jane.raggatt@mater.uq.edu.au.
Batoon L; Blood and Bone Diseases Program, Mater Research Institute - The University of Queensland, Faculty of Medicine and Biomedical Sciences, Translational Research Institute, 37 Kent Street, Woolloongabba, 4102, Australia. Electronic address: lena.batoon@mater.uq.edu.au.
Hume DA; The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Roslin, Midlothian EH25 9PS, Scotland, United Kingdom. Electronic address: david.hume@roslin.ed.ac.uk.
Levesque JP; Blood and Bone Diseases Program, Mater Research Institute - The University of Queensland, Faculty of Medicine and Biomedical Sciences, Translational Research Institute, 37 Kent Street, Woolloongabba, 4102, Australia. Electronic address: jp.levesque@mater.uq.edu.au.
Pettit AR; Blood and Bone Diseases Program, Mater Research Institute - The University of Queensland, Faculty of Medicine and Biomedical Sciences, Translational Research Institute, 37 Kent Street, Woolloongabba, 4102, Australia. Electronic address: allison.pettit@mater.uq.edu.au.

Semin Cell Dev Biol ; 61: 12-21, 2017 01.

Article en En | MEDLINE | ID: mdl-27521519

ABSTRACT

ABSTRACT

Macrophages, named for their phagocytic ability, participate in homeostasis, tissue regeneration and inflammatory responses. Bone and adjacent marrow contain multiple functionally unique resident tissue macrophage subsets which maintain and regulate anatomically distinct niche environments within these interconnected tissues. Three subsets of bone-bone marrow resident tissue macrophages have been characterised; erythroblastic island macrophages, haematopoietic stem cell niche macrophages and osteal macrophages. The role of these macrophages in controlling homeostasis and repair in bone and bone marrow niches is reviewed in detail.

Asunto(s)

Médula Ósea/patología; Huesos/patología; Homeostasis; Macrófagos/patología; Nicho de Células Madre; Cicatrización de Heridas; Animales; Humanos

Palabras clave

Bone and bone marrow; Haematopoiesis; Macrophages; Stem cell niches

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Cicatrización de Heridas / Huesos / Médula Ósea / Nicho de Células Madre / Homeostasis / Macrófagos Límite: Animals / Humans Idioma: En Revista: Semin Cell Dev Biol Asunto de la revista: EMBRIOLOGIA Año: 2017 Tipo del documento: Article

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