Dibutyl phthalate impairs steroidogenesis and a subset of LH-dependent genes in cultured human mural granulosa cell in vitro.

Adir, Michal; Combelles, Catherine M H; Mansur, Abdallah; Ophir, Libby; Hourvitz, Ariel; Orvieto, Raoul; Dor, Jehoshua; Machtinger, Ronit

Adir, Michal; Combelles, Catherine M H; Mansur, Abdallah; Ophir, Libby; Hourvitz, Ariel; Orvieto, Raoul; Dor, Jehoshua; Machtinger, Ronit.

Afiliación

Adir M; Infertility and IVF Unit, Department of Obstetrics and Gynecology, Chaim Sheba Medical Center and Sackler School of Medicine, Tel-Aviv University, Israel.
Combelles CMH; Biology Department, Middlebury College, Middlebury, VT, USA.
Mansur A; Infertility and IVF Unit, Department of Obstetrics and Gynecology, Chaim Sheba Medical Center and Sackler School of Medicine, Tel-Aviv University, Israel.
Ophir L; Infertility and IVF Unit, Department of Obstetrics and Gynecology, Chaim Sheba Medical Center and Sackler School of Medicine, Tel-Aviv University, Israel.
Hourvitz A; Infertility and IVF Unit, Department of Obstetrics and Gynecology, Chaim Sheba Medical Center and Sackler School of Medicine, Tel-Aviv University, Israel.
Orvieto R; Infertility and IVF Unit, Department of Obstetrics and Gynecology, Chaim Sheba Medical Center and Sackler School of Medicine, Tel-Aviv University, Israel.
Dor J; Infertility and IVF Unit, Department of Obstetrics and Gynecology, Chaim Sheba Medical Center and Sackler School of Medicine, Tel-Aviv University, Israel.
Machtinger R; Infertility and IVF Unit, Department of Obstetrics and Gynecology, Chaim Sheba Medical Center and Sackler School of Medicine, Tel-Aviv University, Israel. Electronic address: Ronit.Machtinger@sheba.health.gov.il.

Reprod Toxicol ; 69: 13-18, 2017 04.

Article en En | MEDLINE | ID: mdl-28104404

Asunto(s)

Dibutil Ftalato/toxicidad; Células de la Granulosa/efectos de los fármacos; Adulto; Aromatasa/genética; Betacelulina/genética; Células Cultivadas; Enzima de Desdoblamiento de la Cadena Lateral del Colesterol/genética; Epirregulina/genética; Estradiol/metabolismo; Femenino; Células de la Granulosa/metabolismo; Humanos; Hormona Luteinizante; Fosfoproteínas/genética; Progesterona/metabolismo; ARN Mensajero/metabolismo; Factor A de Crecimiento Endotelial Vascular/genética; Adulto Joven

Palabras clave

Dibutyl phthalate; EGFlike factors; Endocrine disruptors; Granulosa cells; Steroidogenesis

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Dibutil Ftalato / Células de la Granulosa Tipo de estudio: Prognostic_studies Límite: Adult / Female / Humans Idioma: En Revista: Reprod Toxicol Asunto de la revista: EMBRIOLOGIA / MEDICINA REPRODUTIVA / TOXICOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Israel

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