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Custom database development and biomarker discovery methods for MALDI-TOF mass spectrometry-based identification of high-consequence bacterial pathogens.
Tracz, Dobryan M; Tyler, Andrea D; Cunningham, Ian; Antonation, Kym S; Corbett, Cindi R.
Afiliación
  • Tracz DM; National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, Manitoba R3E 3R2, Canada.
  • Tyler AD; National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, Manitoba R3E 3R2, Canada.
  • Cunningham I; National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, Manitoba R3E 3R2, Canada.
  • Antonation KS; National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, Manitoba R3E 3R2, Canada.
  • Corbett CR; National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, Manitoba R3E 3R2, Canada; University of Manitoba, Department of Medical Microbiology and Infectious Diseases, Winnipeg, Manitoba R3E 0J9, Canada. Electronic address: Cindi.Corbett@phac-aspc.gc.ca.
J Microbiol Methods ; 134: 54-57, 2017 03.
Article en En | MEDLINE | ID: mdl-28108323
A high-quality custom database of MALDI-TOF mass spectral profiles was developed with the goal of improving clinical diagnostic identification of high-consequence bacterial pathogens. A biomarker discovery method is presented for identifying and evaluating MALDI-TOF MS spectra to potentially differentiate biothreat bacteria from less-pathogenic near-neighbour species.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Bacterias / Biomarcadores / Técnicas de Tipificación Bacteriana / Espectrometría de Masa por Láser de Matriz Asistida de Ionización Desorción / Bases de Datos de Ácidos Nucleicos Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: J Microbiol Methods Año: 2017 Tipo del documento: Article País de afiliación: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Bacterias / Biomarcadores / Técnicas de Tipificación Bacteriana / Espectrometría de Masa por Láser de Matriz Asistida de Ionización Desorción / Bases de Datos de Ácidos Nucleicos Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: J Microbiol Methods Año: 2017 Tipo del documento: Article País de afiliación: Canadá