Late onset cytopenias following haematopoietic stem cell transplant associated with viral infection and cell specific antibodies.
Transpl Immunol
; 41: 32-36, 2017 03.
Article
en En
| MEDLINE
| ID: mdl-28167271
ABSTRACT
This report describes a patient who received an allogeneic haematopoietic stem cell transplant and who, following a viral infection, developed late onset cytopenias associated with antibodies against red cells, platelets and granulocytes. Investigation of these cytopenias revealed the presence of lineage specific auto- and allo-antibodies, which were not present in either the donor or in the recipient prior to the viral infection. This case provides further evidence for the concept that viral challenges following HSCT can result in the production of cell specific antibodies that can have significant implications for patient management.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Autoanticuerpos
/
Trombocitopenia
/
Virosis
/
Trasplante de Células Madre Hematopoyéticas
/
Agranulocitosis
/
Isoanticuerpos
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Humans
/
Male
Idioma:
En
Revista:
Transpl Immunol
Asunto de la revista:
ALERGIA E IMUNOLOGIA
/
TRANSPLANTE
Año:
2017
Tipo del documento:
Article