Increased Pilus Production Conferred by a Naturally Occurring Mutation Alters Host-Pathogen Interaction in Favor of Carriage in Streptococcus pyogenes.

Flores, Anthony R; Olsen, Randall J; Cantu, Concepcion; Pallister, Kyler B; Guerra, Fermin E; Voyich, Jovanka M; Musser, James M

Flores, Anthony R; Olsen, Randall J; Cantu, Concepcion; Pallister, Kyler B; Guerra, Fermin E; Voyich, Jovanka M; Musser, James M.

Afiliación

Flores AR; Section of Infectious Diseases, Department of Pediatrics, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas, USA arflores@bcm.edu.
Olsen RJ; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, Department of Pathology and Genomic Medicine, Houston Methodist, Houston, Texas, USA.
Cantu C; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, Department of Pathology and Genomic Medicine, Houston Methodist, Houston, Texas, USA.
Pallister KB; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, Department of Pathology and Genomic Medicine, Houston Methodist, Houston, Texas, USA.
Guerra FE; Department of Microbiology and Immunology, Montana State University, Bozeman, Montana, USA.
Voyich JM; Department of Microbiology and Immunology, Montana State University, Bozeman, Montana, USA.
Musser JM; Department of Microbiology and Immunology, Montana State University, Bozeman, Montana, USA.

Infect Immun ; 85(5)2017 05.

Article en En | MEDLINE | ID: mdl-28264907

Asunto(s)

Portador Sano/microbiología; Fimbrias Bacterianas/genética; Histidina Quinasa/genética; Mutación Missense; Biogénesis de Organelos; Infecciones Estreptocócicas/microbiología; Streptococcus pyogenes/patogenicidad; Animales; Adhesión Bacteriana; Células Cultivadas; Células Epiteliales/microbiología; Femenino; Perfilación de la Expresión Génica; Interacciones Huésped-Patógeno; Humanos; Ratones; Viabilidad Microbiana; Nasofaringe/microbiología; Neutrófilos/inmunología; Neutrófilos/microbiología; Streptococcus pyogenes/fisiología; Transcripción Genética

Palabras clave

asymptomatic carriage; carrier; colonization; group A Streptococcus; pilus; sensor kinase

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Infecciones Estreptocócicas / Streptococcus pyogenes / Biogénesis de Organelos / Portador Sano / Fimbrias Bacterianas / Mutación Missense / Histidina Quinasa Límite: Animals / Female / Humans Idioma: En Revista: Infect Immun Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos

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