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Injectable and topical neurotoxins in dermatology: Basic science, anatomy, and therapeutic agents.
Giordano, Cerrene N; Matarasso, Seth L; Ozog, David M.
Afiliación
  • Giordano CN; Department of Dermatology, Henry Ford Hospital, Detroit, Michigan.
  • Matarasso SL; Department of Dermatology, University of California, San Francisco School of Medicine, San Francisco, California.
  • Ozog DM; Department of Dermatology, Henry Ford Hospital, Detroit, Michigan. Electronic address: dozog1@hfhs.org.
J Am Acad Dermatol ; 76(6): 1013-1024, 2017 Jun.
Article en En | MEDLINE | ID: mdl-28522038
Botulinum toxin is a potentially deadly anaerobic bacterial toxin that acts by inhibiting release of acetylcholine at the neuromuscular junction, thereby inhibiting contraction of the exposed striated muscle. There are currently 4 botulinum toxin preparations approved by the US Food and Drug Administration (FDA): onabotulinumtoxin, abobotulinumtoxin, incobotulinumtoxin and rimabotulinumtoxin. While significant overlap exists, each product has unique properties and specifications, including dosing, diffusion, and storage. Extensive physician knowledge of facial anatomy, coupled with key differences of the various neurotoxin types, is essential for safe and successful treatments. The first article in this continuing medical education series reviews key characteristics of each neurotoxin, including new and upcoming agents, and provides an anatomic overview of the most commonly injected cosmetic sites.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Toxinas Botulínicas / Neurotoxinas Límite: Humans Idioma: En Revista: J Am Acad Dermatol Año: 2017 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Toxinas Botulínicas / Neurotoxinas Límite: Humans Idioma: En Revista: J Am Acad Dermatol Año: 2017 Tipo del documento: Article