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Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability.
Zhao, Xuelian; Howell, Katie A; He, Shihua; Brannan, Jennifer M; Wec, Anna Z; Davidson, Edgar; Turner, Hannah L; Chiang, Chi-I; Lei, Lin; Fels, J Maximilian; Vu, Hong; Shulenin, Sergey; Turonis, Ashley N; Kuehne, Ana I; Liu, Guodong; Ta, Mi; Wang, Yimeng; Sundling, Christopher; Xiao, Yongli; Spence, Jennifer S; Doranz, Benjamin J; Holtsberg, Frederick W; Ward, Andrew B; Chandran, Kartik; Dye, John M; Qiu, Xiangguo; Li, Yuxing; Aman, M Javad.
Afiliación
  • Zhao X; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20878, USA.
  • Howell KA; Integrated BioTherapeutics, Rockville, MD 20850, USA.
  • He S; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, Canada; Deparment of Medical Microbiology, University of Manitoba, MB R3E 0J9, Canada.
  • Brannan JM; US Army Medical Research Institute of Infectious Diseases, Frederick, MD 21701, USA.
  • Wec AZ; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Davidson E; Integral Molecular, Philadelphia, PA 19104, USA.
  • Turner HL; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Chiang CI; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20878, USA.
  • Lei L; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20878, USA.
  • Fels JM; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Vu H; Integrated BioTherapeutics, Rockville, MD 20850, USA.
  • Shulenin S; Integrated BioTherapeutics, Rockville, MD 20850, USA.
  • Turonis AN; Integrated BioTherapeutics, Rockville, MD 20850, USA.
  • Kuehne AI; US Army Medical Research Institute of Infectious Diseases, Frederick, MD 21701, USA.
  • Liu G; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, Canada; Deparment of Medical Microbiology, University of Manitoba, MB R3E 0J9, Canada.
  • Ta M; Integral Molecular, Philadelphia, PA 19104, USA.
  • Wang Y; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20878, USA.
  • Sundling C; Immunology Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia.
  • Xiao Y; Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892, USA.
  • Spence JS; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Doranz BJ; Integral Molecular, Philadelphia, PA 19104, USA.
  • Holtsberg FW; Integrated BioTherapeutics, Rockville, MD 20850, USA.
  • Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Chandran K; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Dye JM; US Army Medical Research Institute of Infectious Diseases, Frederick, MD 21701, USA.
  • Qiu X; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, Canada; Deparment of Medical Microbiology, University of Manitoba, MB R3E 0J9, Canada.
  • Li Y; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20878, USA; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA. Electronic address: liy@ibbr.umd.edu.
  • Aman MJ; Integrated BioTherapeutics, Rockville, MD 20850, USA. Electronic address: javad@integratedbiotherapeutics.com.
Cell ; 169(5): 891-904.e15, 2017 May 18.
Article en En | MEDLINE | ID: mdl-28525756
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fiebre Hemorrágica Ebola / Vacunas contra el Virus del Ébola / Anticuerpos Neutralizantes / Anticuerpos Antivirales Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Cell Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fiebre Hemorrágica Ebola / Vacunas contra el Virus del Ébola / Anticuerpos Neutralizantes / Anticuerpos Antivirales Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Cell Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos