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The novel CXCR4 antagonist, PRX177561, reduces tumor cell proliferation and accelerates cancer stem cell differentiation in glioblastoma preclinical models.
Gravina, Giovanni Luca; Mancini, Andrea; Colapietro, Alessandro; Vitale, Flora; Vetuschi, Antonella; Pompili, Simona; Rossi, Giulia; Marampon, Francesco; Richardson, Peter J; Patient, Lee; Patient, Lee; Burbidge, Stephen; Festuccia, Claudio.
Afiliación
  • Gravina GL; 1 Department of Biotechnological and Applied Clinical Sciences, Laboratory of Radiobiology, University of L'Aquila, L'Aquila, Italy.
  • Mancini A; 2 Department of Biotechnological and Applied Clinical Sciences, Division of Radiotherapy, University of L'Aquila, L'Aquila, Italy.
  • Colapietro A; 1 Department of Biotechnological and Applied Clinical Sciences, Laboratory of Radiobiology, University of L'Aquila, L'Aquila, Italy.
  • Vitale F; 1 Department of Biotechnological and Applied Clinical Sciences, Laboratory of Radiobiology, University of L'Aquila, L'Aquila, Italy.
  • Vetuschi A; 3 Department of Biotechnological and Applied Clinical Sciences, Neurobiology Laboratory, University of L'Aquila, L'Aquila, Italy.
  • Pompili S; 4 Department of Biotechnological and Applied Clinical Sciences, Laboratory of Human Anatomy, University of L'Aquila, L'Aquila, Italy.
  • Rossi G; 4 Department of Biotechnological and Applied Clinical Sciences, Laboratory of Human Anatomy, University of L'Aquila, L'Aquila, Italy.
  • Marampon F; 5 Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
  • Richardson PJ; 1 Department of Biotechnological and Applied Clinical Sciences, Laboratory of Radiobiology, University of L'Aquila, L'Aquila, Italy.
  • Patient L; 6 Proximagen Ltd., Cambridge, UK.
  • Patient L; 1 Department of Biotechnological and Applied Clinical Sciences, Laboratory of Radiobiology, University of L'Aquila, L'Aquila, Italy.
  • Burbidge S; 1 Department of Biotechnological and Applied Clinical Sciences, Laboratory of Radiobiology, University of L'Aquila, L'Aquila, Italy.
  • Festuccia C; 6 Proximagen Ltd., Cambridge, UK.
Tumour Biol ; 39(6): 1010428317695528, 2017 Jun.
Article en En | MEDLINE | ID: mdl-28639900
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Glioblastoma / Receptores CXCR4 / Quimiocina CXCL12 / Recurrencia Local de Neoplasia / Neovascularización Patológica Tipo de estudio: Prognostic_studies Límite: Adult / Animals / Humans Idioma: En Revista: Tumour Biol Asunto de la revista: NEOPLASIAS Año: 2017 Tipo del documento: Article País de afiliación: Italia
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Glioblastoma / Receptores CXCR4 / Quimiocina CXCL12 / Recurrencia Local de Neoplasia / Neovascularización Patológica Tipo de estudio: Prognostic_studies Límite: Adult / Animals / Humans Idioma: En Revista: Tumour Biol Asunto de la revista: NEOPLASIAS Año: 2017 Tipo del documento: Article País de afiliación: Italia