Mutations in TYROBP are not a common cause of dementia in a Turkish cohort.

Darwent, Lee; Carmona, Susana; Lohmann, Ebba; Guven, Gamze; Kun-Rodrigues, Celia; Bilgic, Basar; Hanagasi, Hasmet; Gurvit, Hakan; Erginel-Unaltuna, Nihan; Pak, Meltem; Hardy, John; Singleton, Andrew; Brás, Jose; Guerreiro, Rita

Darwent, Lee; Carmona, Susana; Lohmann, Ebba; Guven, Gamze; Kun-Rodrigues, Celia; Bilgic, Basar; Hanagasi, Hasmet; Gurvit, Hakan; Erginel-Unaltuna, Nihan; Pak, Meltem; Hardy, John; Singleton, Andrew; Brás, Jose; Guerreiro, Rita.

Afiliación

Darwent L; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK.
Carmona S; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK.
Lohmann E; Behavioral Neurology and Movement Disorders Unit, Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey; Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen and German Center for Neurodegenerative Disea
Guven G; Genetics Department, Aziz Sancar Institute for Experimental Medicine, Istanbul University, Istanbul, Turkey.
Kun-Rodrigues C; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK.
Bilgic B; Behavioral Neurology and Movement Disorders Unit, Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Hanagasi H; Behavioral Neurology and Movement Disorders Unit, Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Gurvit H; Behavioral Neurology and Movement Disorders Unit, Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Erginel-Unaltuna N; Genetics Department, Aziz Sancar Institute for Experimental Medicine, Istanbul University, Istanbul, Turkey.
Pak M; Behavioral Neurology and Movement Disorders Unit, Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Hardy J; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK.
Singleton A; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Brás J; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK; Department of Medical Sciences, Institute of Biomedicine-iBiMED, University of Aveiro, Aveiro, Portugal; UK Dementia Research Institute at UCL (UK DRI), London, UK.
Guerreiro R; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK; Department of Medical Sciences, Institute of Biomedicine-iBiMED, University of Aveiro, Aveiro, Portugal; UK Dementia Research Institute at UCL (UK DRI), London, UK. Electronic address: r.guerreiro@uc

Neurobiol Aging ; 58: 240.e1-240.e3, 2017 10.

Article en En | MEDLINE | ID: mdl-28716534

Asunto(s)

Proteínas Adaptadoras Transductoras de Señales/genética; Demencia/genética; Estudio de Asociación del Genoma Completo; Proteínas de la Membrana/genética; Mutación/genética; Estudios de Cohortes; Humanos; Glicoproteínas de Membrana/genética; Receptores Inmunológicos/genética; Turquía; Secuenciación del Exoma

Palabras clave

Dementia; Genetic variant; TYROBP; Turkish cohort; Whole-exome sequencing; Whole-genome genotyping

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Demencia / Proteínas Adaptadoras Transductoras de Señales / Estudio de Asociación del Genoma Completo / Proteínas de la Membrana / Mutación Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans País/Región como asunto: Asia Idioma: En Revista: Neurobiol Aging Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido

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