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A human tissue-based functional assay platform to evaluate the immune function impact of small molecule inhibitors that target the immune system.
St Pierre, Cristina; Guo, Jane; Shin, John D; Engstrom, Laura W; Lee, Hyun-Hee; Herbert, Alan; Surdi, Laura; Baker, James; Salmon, Michael; Shah, Sanjiv; Ellis, J Michael; Houshyar, Hani; Crackower, Michael A; Kleinschek, Melanie A; Jones, Dallas C; Hicks, Alexandra; Zaller, Dennis M; Alves, Stephen E; Ramadas, Ravisankar A.
Afiliación
  • St Pierre C; Oncology & Immunology Discovery, Merck Research Laboratories, Boston, MA, United States of America.
  • Guo J; Oncology & Immunology Discovery, Merck Research Laboratories, Boston, MA, United States of America.
  • Shin JD; Oncology & Immunology Discovery, Merck Research Laboratories, Boston, MA, United States of America.
  • Engstrom LW; Oncology & Immunology Discovery, Merck Research Laboratories, Boston, MA, United States of America.
  • Lee HH; Oncology & Immunology Discovery, Merck Research Laboratories, Boston, MA, United States of America.
  • Herbert A; Genetics and Pharmacogenomics, Merck Research Laboratories, Boston, MA, United States of America.
  • Surdi L; Drug Metabolism and Pharmacokinetics, Merck Research Laboratories, Boston, MA, United States of America.
  • Baker J; Drug Metabolism and Pharmacokinetics, Merck Research Laboratories, Boston, MA, United States of America.
  • Salmon M; Oncology & Immunology Discovery, Merck Research Laboratories, Boston, MA, United States of America.
  • Shah S; Pharmacology, Merck Research Laboratories, Boston, MA, United States of America.
  • Ellis JM; Exploratory Chemistry, Merck Research Laboratories, Boston, MA, United States of America.
  • Houshyar H; Oncology & Immunology Discovery, Merck Research Laboratories, Boston, MA, United States of America.
  • Crackower MA; Oncology & Immunology Discovery, Merck Research Laboratories, Boston, MA, United States of America.
  • Kleinschek MA; Oncology & Immunology Discovery, Merck Research Laboratories, Boston, MA, United States of America.
  • Jones DC; Oncology & Immunology Discovery, Merck Research Laboratories, Boston, MA, United States of America.
  • Hicks A; Oncology & Immunology Discovery, Merck Research Laboratories, Boston, MA, United States of America.
  • Zaller DM; Oncology & Immunology Discovery, Merck Research Laboratories, Boston, MA, United States of America.
  • Alves SE; Oncology & Immunology Discovery, Merck Research Laboratories, Boston, MA, United States of America.
  • Ramadas RA; Oncology & Immunology Discovery, Merck Research Laboratories, Boston, MA, United States of America.
PLoS One ; 12(7): e0180870, 2017.
Article en En | MEDLINE | ID: mdl-28719615
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Evaluación Preclínica de Medicamentos / Bibliotecas de Moléculas Pequeñas / Sistema Inmunológico Tipo de estudio: Prognostic_studies / Qualitative_research Límite: Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Evaluación Preclínica de Medicamentos / Bibliotecas de Moléculas Pequeñas / Sistema Inmunológico Tipo de estudio: Prognostic_studies / Qualitative_research Límite: Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos