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Multicellular Vascularized Engineered Tissues through User-Programmable Biomaterial Photodegradation.
Arakawa, Christopher K; Badeau, Barry A; Zheng, Ying; DeForest, Cole A.
Afiliación
  • Arakawa CK; Department of Bioengineering, University of Washington, 3720 15th Ave NE, Seattle, WA, 98105, USA.
  • Badeau BA; Department of Chemical Engineering, University of Washington, 3781, Okanogan Lane NE, Seattle, WA, 98195, USA.
  • Zheng Y; Department of Bioengineering, University of Washington, 3720 15th Ave NE, Seattle, WA, 98105, USA.
  • DeForest CA; Institute for Stem Cell and Regenerative Medicine, University of Washington, 850 Republican Street, Seattle, WA, 98109, USA.
Adv Mater ; 29(37)2017 Oct.
Article en En | MEDLINE | ID: mdl-28737278
ABSTRACT
A photodegradable material-based approach to generate endothelialized 3D vascular networks within cell-laden hydrogel biomaterials is introduced. Exploiting multiphoton lithography, microchannel networks spanning nearly all size scales of native human vasculature are readily generated with unprecedented user-defined 4D control. Intraluminal channel architectures of synthetic vessels are fully customizable, providing new opportunities for next-generation microfluidics and directed cell function.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ingeniería de Tejidos Límite: Humans Idioma: En Revista: Adv Mater Asunto de la revista: BIOFISICA / QUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ingeniería de Tejidos Límite: Humans Idioma: En Revista: Adv Mater Asunto de la revista: BIOFISICA / QUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos