Perturbations of NAD<sup>+</sup> salvage systems impact mitochondrial function and energy homeostasis in mouse myoblasts and intact skeletal muscle.

Agerholm, Marianne; Dall, Morten; Jensen, Benjamin A H; Prats, Clara; Madsen, Søren; Basse, Astrid L; Graae, Anne-Sofie; Risis, Steve; Goldenbaum, Julie; Quistorff, Bjørn; Larsen, Steen; Vienberg, Sara G; Treebak, Jonas T

Perturbations of NAD⁺ salvage systems impact mitochondrial function and energy homeostasis in mouse myoblasts and intact skeletal muscle.

Agerholm, Marianne; Dall, Morten; Jensen, Benjamin A H; Prats, Clara; Madsen, Søren; Basse, Astrid L; Graae, Anne-Sofie; Risis, Steve; Goldenbaum, Julie; Quistorff, Bjørn; Larsen, Steen; Vienberg, Sara G; Treebak, Jonas T.

Afiliación

Agerholm M; Section of Integrative Physiology, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen , Copenhagen , Denmark.
Dall M; Section of Integrative Physiology, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen , Copenhagen , Denmark.
Jensen BAH; Laboratory of Genomics and Molecular Biomedicine, Department of Biology, University of Copenhagen , Copenhagen , Denmark.
Prats C; Xlab, Center for Healthy Aging, Department of Biomedical Sciences, University of Copenhagen , Copenhagen , Denmark.
Madsen S; Section of Integrative Physiology, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen , Copenhagen , Denmark.
Basse AL; Section of Integrative Physiology, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen , Copenhagen , Denmark.
Graae AS; Section of Integrative Physiology, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen , Copenhagen , Denmark.
Risis S; Section of Integrative Physiology, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen , Copenhagen , Denmark.
Goldenbaum J; Section of Integrative Physiology, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen , Copenhagen , Denmark.
Quistorff B; Section for Translational Metabolic Physiology, Novo Nordisk Foundation Center for Basic Metabolic Research, and Department of Biomedical Sciences, University of Copenhagen , Copenhagen , Denmark.
Larsen S; Xlab, Center for Healthy Aging, Department of Biomedical Sciences, University of Copenhagen , Copenhagen , Denmark.
Vienberg SG; Section of Integrative Physiology, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen , Copenhagen , Denmark.
Treebak JT; Section of Integrative Physiology, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen , Copenhagen , Denmark.

Am J Physiol Endocrinol Metab ; 314(4): E377-E395, 2018 04 01.

Article en En | MEDLINE | ID: mdl-29208611

Asunto(s)

Citocinas/genética; Metabolismo Energético/genética; Mitocondrias Musculares/fisiología; Músculo Esquelético/metabolismo; Mioblastos/metabolismo; NAD/metabolismo; Nicotinamida Fosforribosiltransferasa/genética; Animales; Metabolismo de los Hidratos de Carbono/genética; Células Cultivadas; Citocinas/metabolismo; Homeostasis/genética; Masculino; Ratones; Ratones Endogámicos C57BL; Ratones Transgénicos; Nicotinamida Fosforribosiltransferasa/metabolismo; Fosforilación Oxidativa; Transducción de Señal/genética

Palabras clave

HIF-1α; NAMPT; SIRT6; glycolysis; nicotinamide riboside

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Citocinas / Músculo Esquelético / Mioblastos / Metabolismo Energético / Nicotinamida Fosforribosiltransferasa / Mitocondrias Musculares / NAD Límite: Animals Idioma: En Revista: Am J Physiol Endocrinol Metab Asunto de la revista: ENDOCRINOLOGIA / FISIOLOGIA / METABOLISMO Año: 2018 Tipo del documento: Article País de afiliación: Dinamarca

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