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Preliminary aggregate safety and immunogenicity results from three trials of a purified inactivated Zika virus vaccine candidate: phase 1, randomised, double-blind, placebo-controlled clinical trials.
Modjarrad, Kayvon; Lin, Leyi; George, Sarah L; Stephenson, Kathryn E; Eckels, Kenneth H; De La Barrera, Rafael A; Jarman, Richard G; Sondergaard, Erica; Tennant, Janice; Ansel, Jessica L; Mills, Kristin; Koren, Michael; Robb, Merlin L; Barrett, Jill; Thompson, Jason; Kosel, Alison E; Dawson, Peter; Hale, Andrew; Tan, C Sabrina; Walsh, Stephen R; Meyer, Keith E; Brien, James; Crowell, Trevor A; Blazevic, Azra; Mosby, Karla; Larocca, Rafael A; Abbink, Peter; Boyd, Michael; Bricault, Christine A; Seaman, Michael S; Basil, Anne; Walsh, Melissa; Tonwe, Veronica; Hoft, Daniel F; Thomas, Stephen J; Barouch, Dan H; Michael, Nelson L.
Afiliación
  • Modjarrad K; Walter Reed Army Institute of Research, Silver Spring, MD, USA.
  • Lin L; Walter Reed Army Institute of Research, Silver Spring, MD, USA.
  • George SL; Department of Internal Medicine, Division of Infectious Diseases, Allergy and Immunology, Saint Louis University School of Medicine, Saint Louis, MO, USA; Saint Louis VA Medical Center, Saint Louis, MO, USA.
  • Stephenson KE; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.
  • Eckels KH; Walter Reed Army Institute of Research, Silver Spring, MD, USA.
  • De La Barrera RA; Walter Reed Army Institute of Research, Silver Spring, MD, USA.
  • Jarman RG; Walter Reed Army Institute of Research, Silver Spring, MD, USA.
  • Sondergaard E; Walter Reed Army Institute of Research, Silver Spring, MD, USA.
  • Tennant J; Department of Internal Medicine, Division of Infectious Diseases, Allergy and Immunology, Saint Louis University School of Medicine, Saint Louis, MO, USA.
  • Ansel JL; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Mills K; Walter Reed Army Institute of Research, Silver Spring, MD, USA.
  • Koren M; Walter Reed Army Institute of Research, Silver Spring, MD, USA.
  • Robb ML; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
  • Barrett J; Emmes Corporation, Rockville, MD, USA.
  • Thompson J; Emmes Corporation, Rockville, MD, USA.
  • Kosel AE; Emmes Corporation, Rockville, MD, USA.
  • Dawson P; Emmes Corporation, Rockville, MD, USA.
  • Hale A; University of Vermont Medical Center and Larner College of Medicine, Burlington, VT, USA.
  • Tan CS; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Walsh SR; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Meyer KE; Department of Internal Medicine, Division of Infectious Diseases, Allergy and Immunology, Saint Louis University School of Medicine, Saint Louis, MO, USA.
  • Brien J; Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, Saint Louis, MO, USA.
  • Crowell TA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
  • Blazevic A; Department of Internal Medicine, Division of Infectious Diseases, Allergy and Immunology, Saint Louis University School of Medicine, Saint Louis, MO, USA.
  • Mosby K; Department of Internal Medicine, Division of Infectious Diseases, Allergy and Immunology, Saint Louis University School of Medicine, Saint Louis, MO, USA.
  • Larocca RA; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Abbink P; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Boyd M; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Bricault CA; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Seaman MS; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Basil A; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
  • Walsh M; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
  • Tonwe V; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
  • Hoft DF; Department of Internal Medicine, Division of Infectious Diseases, Allergy and Immunology, Saint Louis University School of Medicine, Saint Louis, MO, USA; Saint Louis VA Medical Center, Saint Louis, MO, USA.
  • Thomas SJ; Walter Reed Army Institute of Research, Silver Spring, MD, USA.
  • Barouch DH; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA. Electronic address: dbarouch@bidmc.harvard.edu.
  • Michael NL; Walter Reed Army Institute of Research, Silver Spring, MD, USA. Electronic address: nelson.l.michael2.mil@mail.mil.
Lancet ; 391(10120): 563-571, 2018 02 10.
Article en En | MEDLINE | ID: mdl-29217375
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Vacunas Virales / Anticuerpos Neutralizantes / Virus Zika / Anticuerpos Antivirales Tipo de estudio: Clinical_trials Límite: Humans Idioma: En Revista: Lancet Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Vacunas Virales / Anticuerpos Neutralizantes / Virus Zika / Anticuerpos Antivirales Tipo de estudio: Clinical_trials Límite: Humans Idioma: En Revista: Lancet Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos