Computational approach to discriminate human and mouse sequences in patient-derived tumour xenografts.

Callari, Maurizio; Batra, Ankita Sati; Batra, Rajbir Nath; Sammut, Stephen-John; Greenwood, Wendy; Clifford, Harry; Hercus, Colin; Chin, Suet-Feung; Bruna, Alejandra; Rueda, Oscar M; Caldas, Carlos

Callari, Maurizio; Batra, Ankita Sati; Batra, Rajbir Nath; Sammut, Stephen-John; Greenwood, Wendy; Clifford, Harry; Hercus, Colin; Chin, Suet-Feung; Bruna, Alejandra; Rueda, Oscar M; Caldas, Carlos.

Afiliación

Callari M; CRUK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.
Batra AS; CRUK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.
Batra RN; CRUK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.
Sammut SJ; CRUK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.
Greenwood W; CRUK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.
Clifford H; CRUK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.
Hercus C; Novocraft Technologies Sdn Bhd, C-23A-05, 3 Two Square, Jalan 19/1, Section 19, 46300, Petaling Jaya, Selangor Darul Ehsan, Malaysia.
Chin SF; CRUK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.
Bruna A; CRUK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.
Rueda OM; CRUK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.
Caldas C; CRUK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK. carlos.caldas@cruk.cam.ac.uk.

BMC Genomics ; 19(1): 19, 2018 01 05.

Article en En | MEDLINE | ID: mdl-29304755

Asunto(s)

Genómica/métodos; Secuenciación de Nucleótidos de Alto Rendimiento/métodos; Ensayos Antitumor por Modelo de Xenoinjerto; Animales; Neoplasias de la Mama/genética; Neoplasias de la Mama/metabolismo; Perfilación de la Expresión Génica; Humanos; Ratones; Mutación; Alineación de Secuencia; Análisis de Secuencia de ADN; Análisis de Secuencia de ARN

Palabras clave

Alignment; High throughput sequencing; ICRG; In silico combined human-mouse reference genome; Mouse stroma; Patient-derived tumour xenografts; Short-reads

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ensayos Antitumor por Modelo de Xenoinjerto / Genómica / Secuenciación de Nucleótidos de Alto Rendimiento Tipo de estudio: Evaluation_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: BMC Genomics Asunto de la revista: GENETICA Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido

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