Antagonism of Integrin CD11b Affords Protection against Endotoxin Shock and Polymicrobial Sepsis via Attenuation of HMGB1 Nucleocytoplasmic Translocation and Extracellular Release.

Zhou, Huiting; Li, Yanhong; Gui, Huan; Zhao, He; Wu, Ming; Li, Gang; Li, Yiping; Bai, Zhenjiang; Yin, Zhimin; Redmond, H Paul; Wang, Jian; Wang, Jiang Huai; Zhao, Zhihui

Zhou, Huiting; Li, Yanhong; Gui, Huan; Zhao, He; Wu, Ming; Li, Gang; Li, Yiping; Bai, Zhenjiang; Yin, Zhimin; Redmond, H Paul; Wang, Jian; Wang, Jiang Huai; Zhao, Zhihui.

Afiliación

Zhou H; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou 215025, China.
Li Y; Jiangsu Province Key Laboratory for Molecular and Medicine Biotechnology, College of Life Science, Nanjing Normal University, Nanjing 210023, China; and.
Gui H; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou 215025, China.
Zhao H; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou 215025, China.
Wu M; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou 215025, China.
Li G; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou 215025, China.
Li Y; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou 215025, China.
Bai Z; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou 215025, China.
Yin Z; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou 215025, China.
Redmond HP; Jiangsu Province Key Laboratory for Molecular and Medicine Biotechnology, College of Life Science, Nanjing Normal University, Nanjing 210023, China; and.
Wang J; Department of Academic Surgery, University College Cork, Cork University Hospital, Cork T12YN60, Ireland.
Wang JH; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou 215025, China; wj196312@vip.163.com jh.wang@ucc.ie zhaozhihui_1964@aliyun.com.
Zhao Z; Department of Academic Surgery, University College Cork, Cork University Hospital, Cork T12YN60, Ireland wj196312@vip.163.com jh.wang@ucc.ie zhaozhihui_1964@aliyun.com.

J Immunol ; 200(5): 1771-1780, 2018 03 01.

Article en En | MEDLINE | ID: mdl-29343555

Asunto(s)

Antígeno CD11b/metabolismo; Núcleo Celular/metabolismo; Citoplasma/metabolismo; Proteína HMGB1/metabolismo; Transporte de Proteínas/fisiología; Sepsis/metabolismo; Choque Séptico/metabolismo; Animales; Línea Celular; Integrinas/metabolismo; Macrófagos/metabolismo; Masculino; Ratones; Ratones Endogámicos C57BL

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Choque Séptico / Núcleo Celular / Sepsis / Transporte de Proteínas / Citoplasma / Proteína HMGB1 / Antígeno CD11b Límite: Animals Idioma: En Revista: J Immunol Año: 2018 Tipo del documento: Article País de afiliación: China

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