Sleep characteristics and progression of coronary artery calcification: Results from the Heinz Nixdorf Recall cohort study.
Atherosclerosis
; 271: 45-52, 2018 04.
Article
en En
| MEDLINE
| ID: mdl-29459265
ABSTRACT
BACKGROUND AND AIMS:
Sleep characteristics are associated with incident cardiovascular diseases (CVD), but there is a lack of studies on the association between sleep characteristics and incidence/progression of coronary artery calcification (CAC).METHODS:
In the Heinz Nixdorf Recall Study, a population-based cohort study in Germany, CAC was assessed by electron-beam tomography at baseline and at 5-year follow-up. In an analysis set of 3043 subjects (age at baseline 45-74 years; 47% men), we fitted logistic and linear regression models to assess associations between self-rated sleep characteristics (nocturnal and total sleep duration; napping; various sleep disorders) and CAC incidence/CAC progression. Progression was measured as 5-year progression factor, as categories of absolute CAC change, and additionally characterized as rapid or slow compared to an extrapolation of baseline CAC values.RESULTS:
We observed barely any association between sleep characteristics and CAC progression regardless of the chosen statistical approach; associations between sleep and CAC incidence were slightly larger, e.g., the geometric mean of the 5-year CAC progression factor was 6.8% (95% confidence interval -9.5; 25.9) larger for ≤5â¯h, 2.9% (-7.3; 14.3) larger for 5.1-6.9â¯h and 7.1% (-2.4; 15.7) smaller for ≥7.5â¯h total sleep compared to 7- <7.5â¯h total sleep. For subjects with any regular sleep disorder, the geometric mean of the 5-year CAC progression was 3.5% (-4.7; 11.2) smaller compared to subjects without any regular sleep disorder.CONCLUSIONS:
In this German cohort study, sleep characteristics were barely associated with CAC progression.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Sueño
/
Trastornos del Sueño-Vigilia
/
Enfermedad de la Arteria Coronaria
/
Calcificación Vascular
Tipo de estudio:
Clinical_trials
/
Diagnostic_studies
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
Atherosclerosis
Año:
2018
Tipo del documento:
Article