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Family-wide analysis of aminoacyl-sulfamoyl-3-deazaadenosine analogues as inhibitors of aminoacyl-tRNA synthetases.
Zhang, Baole; De Graef, Steff; Nautiyal, Manesh; Pang, Luping; Gadakh, Bharat; Froeyen, Matheus; Van Mellaert, Lieve; Strelkov, Sergei V; Weeks, Stephen D; Van Aerschot, Arthur.
Afiliación
  • Zhang B; Medicinal Chemistry, Rega Institute for Medical Research, KU Leuven, Herestraat 49 Box 1041, B-3000 Leuven, Belgium.
  • De Graef S; Laboratory for Biocrystallography, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Herestraat 49 Box 822, B-3000 Leuven, Belgium.
  • Nautiyal M; Medicinal Chemistry, Rega Institute for Medical Research, KU Leuven, Herestraat 49 Box 1041, B-3000 Leuven, Belgium.
  • Pang L; Medicinal Chemistry, Rega Institute for Medical Research, KU Leuven, Herestraat 49 Box 1041, B-3000 Leuven, Belgium; Laboratory for Biocrystallography, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Herestraat 49 Box 822, B-3000 Leuven, Belgium.
  • Gadakh B; Medicinal Chemistry, Rega Institute for Medical Research, KU Leuven, Herestraat 49 Box 1041, B-3000 Leuven, Belgium.
  • Froeyen M; Medicinal Chemistry, Rega Institute for Medical Research, KU Leuven, Herestraat 49 Box 1041, B-3000 Leuven, Belgium.
  • Van Mellaert L; Laboratory Molecular Bacteriology, Rega Institute for Medical Research, KU Leuven, Herestraat 49 Box 1037, B-3000 Leuven, Belgium.
  • Strelkov SV; Laboratory for Biocrystallography, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Herestraat 49 Box 822, B-3000 Leuven, Belgium.
  • Weeks SD; Laboratory for Biocrystallography, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Herestraat 49 Box 822, B-3000 Leuven, Belgium.
  • Van Aerschot A; Medicinal Chemistry, Rega Institute for Medical Research, KU Leuven, Herestraat 49 Box 1041, B-3000 Leuven, Belgium. Electronic address: arthur.vanaerschot@kuleuven.be.
Eur J Med Chem ; 148: 384-396, 2018 Mar 25.
Article en En | MEDLINE | ID: mdl-29477072

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tubercidina / Aminoacil-ARNt Sintetasas / Antiinfecciosos Idioma: En Revista: Eur J Med Chem Año: 2018 Tipo del documento: Article País de afiliación: Bélgica

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tubercidina / Aminoacil-ARNt Sintetasas / Antiinfecciosos Idioma: En Revista: Eur J Med Chem Año: 2018 Tipo del documento: Article País de afiliación: Bélgica