Tumor-Induced Myeloid Cells Are Reduced by Gemcitabine-Loaded PAMAM Dendrimers Decorated with Anti-Flt1 Antibody.

Yoyen-Ermis, Digdem; Ozturk, Kivilcim; Kursunel, M Alper; Aydin, Cisel; Ozkazanc, Didem; Gurbuz, Mustafa Ulvi; Uner, Aysegul; Tulu, Metin; Calis, Sema; Esendagli, Gunes

Yoyen-Ermis, Digdem; Ozturk, Kivilcim; Kursunel, M Alper; Aydin, Cisel; Ozkazanc, Didem; Gurbuz, Mustafa Ulvi; Uner, Aysegul; Tulu, Metin; Calis, Sema; Esendagli, Gunes.

Afiliación

Yoyen-Ermis D; Cancer Institute, Department of Basic Oncology , Hacettepe University , 06100 Ankara , Turkey.
Ozturk K; Faculty of Pharmacy, Department of Pharmaceutical Technology , Hacettepe University , 06230 Ankara , Turkey.
Kursunel MA; Cancer Institute, Department of Basic Oncology , Hacettepe University , 06100 Ankara , Turkey.
Aydin C; Medical Faculty, Department of Pathology , Hacettepe University , 06100 Ankara , Turkey.
Ozkazanc D; Cancer Institute, Department of Basic Oncology , Hacettepe University , 06100 Ankara , Turkey.
Gurbuz MU; Faculty of Arts and Sciences, Department of Chemistry , Yildiz Technical University , 34349 Istanbul , Turkey.
Uner A; Medical Faculty, Department of Pathology , Hacettepe University , 06100 Ankara , Turkey.
Tulu M; Faculty of Arts and Sciences, Department of Chemistry , Yildiz Technical University , 34349 Istanbul , Turkey.
Calis S; Faculty of Pharmacy, Department of Pharmaceutical Technology , Hacettepe University , 06230 Ankara , Turkey.
Esendagli G; Cancer Institute, Department of Basic Oncology , Hacettepe University , 06100 Ankara , Turkey.

Mol Pharm ; 15(4): 1526-1533, 2018 04 02.

Article en En | MEDLINE | ID: mdl-29481086

Asunto(s)

Dendrímeros/química; Desoxicitidina/análogos & derivados; Células Mieloides/efectos de los fármacos; Neoplasias Pancreáticas/metabolismo; Receptor 1 de Factores de Crecimiento Endotelial Vascular/metabolismo; Animales; Línea Celular Tumoral; Desoxicitidina/química; Desoxicitidina/farmacología; Sistemas de Liberación de Medicamentos; Humanos; Masculino; Ratones; Ratones Desnudos; Polietilenglicoles/química; Distribución Tisular; Gemcitabina

Palabras clave

PAMAM; cancer; dendrimer; drug delivery; myeloid cells

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Células Mieloides / Receptor 1 de Factores de Crecimiento Endotelial Vascular / Desoxicitidina / Dendrímeros Límite: Animals / Humans / Male Idioma: En Revista: Mol Pharm Asunto de la revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Turquía

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