Pharmacological characterization of the cannabinoid receptor 2 agonist, ß-caryophyllene on seizure models in mice.

Tchekalarova, Jana; da Conceição Machado, Keylla; Gomes Júnior, Antonio Luiz; de Carvalho Melo Cavalcante, Ana Amélia; Momchilova, Albena; Tzoneva, Rumyana

Tchekalarova, Jana; da Conceição Machado, Keylla; Gomes Júnior, Antonio Luiz; de Carvalho Melo Cavalcante, Ana Amélia; Momchilova, Albena; Tzoneva, Rumyana.

Afiliación

Tchekalarova J; Institute of Neurobiology, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., Bl. 23, Sofia, 1113, Bulgaria. Electronic address: jane@bio.bas.bg.
da Conceição Machado K; Laboratory of Research in Experimental Neurochemistry of the Postgraduate Program in Pharmaceutical Sciences, Federal University of Piauí, Teresina, Brazil; Laboratory of Research in Toxicological Genetics of the Post-Graduate Program in Pharmaceutical Sciences, Federal University of Piauí, Teresina
Gomes Júnior AL; Laboratory of Research in Experimental Neurochemistry of the Postgraduate Program in Pharmaceutical Sciences, Federal University of Piauí, Teresina, Brazil; Laboratory of Research in Toxicological Genetics of the Post-Graduate Program in Pharmaceutical Sciences, Federal University of Piauí, Teresina
de Carvalho Melo Cavalcante AA; Program of Post-Graduation in Biotechnology (RENORBIO) of the Federal University of Piauí, CEP: 64049-550, Teresina, Brazil.
Momchilova A; Institute of Biophysics and Biomedical Engineering, BAS, Sofia, Bulgaria.
Tzoneva R; Institute of Biophysics and Biomedical Engineering, BAS, Sofia, Bulgaria.

Seizure ; 57: 22-26, 2018 Apr.

Article en En | MEDLINE | ID: mdl-29547827

Asunto(s)

Anticonvulsivantes/farmacología; Agonistas de Receptores de Cannabinoides/farmacología; Receptor Cannabinoide CB2/agonistas; Convulsiones/tratamiento farmacológico; Sesquiterpenos/farmacología; Animales; Diazepam/farmacología; Modelos Animales de Enfermedad; Relación Dosis-Respuesta a Droga; Electrochoque; Hipocampo/efectos de los fármacos; Hipocampo/metabolismo; Ácido Kaínico; Masculino; Malondialdehído/metabolismo; Aprendizaje por Laberinto/efectos de los fármacos; Ratones Endogámicos ICR; Actividad Motora/efectos de los fármacos; Pentilenotetrazol; Fenitoína/farmacología; Sesquiterpenos Policíclicos; Receptor Cannabinoide CB2/metabolismo; Convulsiones/metabolismo; Estado Epiléptico/tratamiento farmacológico; Estado Epiléptico/metabolismo

Palabras clave

CB2 receptor agonist; Kainic acid; MES test; Mice; Oxidative stress; scPTZ test

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Convulsiones / Sesquiterpenos / Receptor Cannabinoide CB2 / Agonistas de Receptores de Cannabinoides / Anticonvulsivantes Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Seizure Asunto de la revista: NEUROLOGIA Año: 2018 Tipo del documento: Article

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