Deoxynivalenol as potential modulator of human steroidogenesis.
J Appl Toxicol
; 38(12): 1450-1459, 2018 12.
Article
en En
| MEDLINE
| ID: mdl-29611633
ABSTRACT
Deoxynivalenol (DON) is a type B trichothecene, produced by the Fusarium species. Exposure to DON might cause disruptive effects such as reduced weight gain, neuroendocrine changes and immune modulation in animals (rats, dogs, pigs). There is huge concern that similar effects can be observed in humans. DON is a potential regulator of intracellular steroidogenesis. It is also possible that DON will be involved in the regulation of miRNAs connected with steroidogenesis. This review summarizes the latest knowledge about the influence of DON on steroidogenesis and human hormonal balance.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Esteroides
/
Tricotecenos
/
Disruptores Endocrinos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
J Appl Toxicol
Año:
2018
Tipo del documento:
Article
País de afiliación:
Polonia