Recapitulating spatiotemporal tumor heterogeneity in vitro through engineered breast cancer microtissues.

Mazio, Claudia; Casale, Costantino; Imparato, Giorgia; Urciuolo, Francesco; Netti, Paolo Antonio

Mazio, Claudia; Casale, Costantino; Imparato, Giorgia; Urciuolo, Francesco; Netti, Paolo Antonio.

Afiliación

Mazio C; Center for Advanced Biomaterials for Health Care@CRIB Istituto Italiano di Tecnologia, Largo Barsanti e Matteucci n. 53, 80125 Napoli, Italy.
Casale C; Interdisciplinary Research Centre on Biomaterials (CRIB), University of Napoli Federico II, P.le Tecchio 80, 80125 Napoli, Italy.
Imparato G; Center for Advanced Biomaterials for Health Care@CRIB Istituto Italiano di Tecnologia, Largo Barsanti e Matteucci n. 53, 80125 Napoli, Italy. Electronic address: giorgia.imparato@iit.it.
Urciuolo F; Center for Advanced Biomaterials for Health Care@CRIB Istituto Italiano di Tecnologia, Largo Barsanti e Matteucci n. 53, 80125 Napoli, Italy; Department of Chemical, Materials and Industrial Production Engineering (DICMAPI), University of Napoli Federico II, P.le Tecchio 80, 80125 Napoli, Italy.
Netti PA; Center for Advanced Biomaterials for Health Care@CRIB Istituto Italiano di Tecnologia, Largo Barsanti e Matteucci n. 53, 80125 Napoli, Italy; Interdisciplinary Research Centre on Biomaterials (CRIB), University of Napoli Federico II, P.le Tecchio 80, 80125 Napoli, Italy; Department of Chemical, Mate

Acta Biomater ; 73: 236-249, 2018 06.

Article en En | MEDLINE | ID: mdl-29679778

Asunto(s)

Neoplasias de la Mama; Fibroblastos; Células Endoteliales de la Vena Umbilical Humana; Modelos Biológicos; Organoides; Microambiente Tumoral; Neoplasias de la Mama/metabolismo; Neoplasias de la Mama/patología; Femenino; Fibroblastos/metabolismo; Fibroblastos/patología; Células Endoteliales de la Vena Umbilical Humana/metabolismo; Células Endoteliales de la Vena Umbilical Humana/patología; Humanos; Células MCF-7; Organoides/metabolismo; Organoides/patología

Palabras clave

3D model; Angiogenesis; Breast cancer; Desmoplastic reaction; Heterogeneity; Microenvironment

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Organoides / Microambiente Tumoral / Células Endoteliales de la Vena Umbilical Humana / Fibroblastos / Modelos Biológicos Límite: Female / Humans Idioma: En Revista: Acta Biomater Año: 2018 Tipo del documento: Article País de afiliación: Italia

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