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Characterization of 3 Novel Tau Radiopharmaceuticals, 11C-RO-963, 11C-RO-643, and 18F-RO-948, in Healthy Controls and in Alzheimer Subjects.
Wong, Dean F; Comley, Robert A; Kuwabara, Hiroto; Rosenberg, Paul B; Resnick, Susan M; Ostrowitzki, Susanne; Vozzi, Cristina; Boess, Frank; Oh, Esther; Lyketsos, Constantine G; Honer, Michael; Gobbi, Luca; Klein, Gregory; George, Noble; Gapasin, Lorena; Kitzmiller, Kelly; Roberts, Josh; Sevigny, Jeff; Nandi, Ayon; Brasic, James; Mishra, Chakradhar; Thambisetty, Madhav; Mogekar, Abhay; Mathur, Anil; Albert, Marilyn; Dannals, Robert F; Borroni, Edilio.
Afiliación
  • Wong DF; Section of High Resolution Brain PET, Department of Radiology and Radiological Sciences and Department of Nuclear Medicine, Johns Hopkins University, Baltimore, Maryland dfwong@jhmi.edu edilio.borroni@roche.com.
  • Comley RA; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland.
  • Kuwabara H; Department of Neuroscience, Johns Hopkins University, Baltimore, Maryland.
  • Rosenberg PB; Department of Neurology, Johns Hopkins University, Baltimore, Maryland.
  • Resnick SM; Pharma Research and Early Development, Hoffmann-La Roche, Basel, Switzerland.
  • Ostrowitzki S; Section of High Resolution Brain PET, Department of Radiology and Radiological Sciences and Department of Nuclear Medicine, Johns Hopkins University, Baltimore, Maryland.
  • Vozzi C; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland.
  • Boess F; Department of Medicine, Johns Hopkins University, Baltimore, Maryland; and.
  • Oh E; Pharma Research and Early Development, Hoffmann-La Roche, Basel, Switzerland.
  • Lyketsos CG; Pharma Research and Early Development, Hoffmann-La Roche, Basel, Switzerland.
  • Honer M; Pharma Research and Early Development, Hoffmann-La Roche, Basel, Switzerland.
  • Gobbi L; Lab of Behavior and Neuroscience, NIH-NIA IRP, Baltimore, Maryland.
  • Klein G; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland.
  • George N; Pharma Research and Early Development, Hoffmann-La Roche, Basel, Switzerland.
  • Gapasin L; Pharma Research and Early Development, Hoffmann-La Roche, Basel, Switzerland.
  • Kitzmiller K; Pharma Research and Early Development, Hoffmann-La Roche, Basel, Switzerland.
  • Roberts J; Section of High Resolution Brain PET, Department of Radiology and Radiological Sciences and Department of Nuclear Medicine, Johns Hopkins University, Baltimore, Maryland.
  • Sevigny J; Section of High Resolution Brain PET, Department of Radiology and Radiological Sciences and Department of Nuclear Medicine, Johns Hopkins University, Baltimore, Maryland.
  • Nandi A; Section of High Resolution Brain PET, Department of Radiology and Radiological Sciences and Department of Nuclear Medicine, Johns Hopkins University, Baltimore, Maryland.
  • Brasic J; Section of High Resolution Brain PET, Department of Radiology and Radiological Sciences and Department of Nuclear Medicine, Johns Hopkins University, Baltimore, Maryland.
  • Mishra C; Pharma Research and Early Development, Hoffmann-La Roche, Basel, Switzerland.
  • Thambisetty M; Section of High Resolution Brain PET, Department of Radiology and Radiological Sciences and Department of Nuclear Medicine, Johns Hopkins University, Baltimore, Maryland.
  • Mogekar A; Section of High Resolution Brain PET, Department of Radiology and Radiological Sciences and Department of Nuclear Medicine, Johns Hopkins University, Baltimore, Maryland.
  • Mathur A; Section of High Resolution Brain PET, Department of Radiology and Radiological Sciences and Department of Nuclear Medicine, Johns Hopkins University, Baltimore, Maryland.
  • Albert M; Lab of Behavior and Neuroscience, NIH-NIA IRP, Baltimore, Maryland.
  • Dannals RF; Department of Neurology, Johns Hopkins University, Baltimore, Maryland.
  • Borroni E; Section of High Resolution Brain PET, Department of Radiology and Radiological Sciences and Department of Nuclear Medicine, Johns Hopkins University, Baltimore, Maryland.
J Nucl Med ; 59(12): 1869-1876, 2018 12.
Article en En | MEDLINE | ID: mdl-29728519
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas tau / Radiofármacos / Tomografía de Emisión de Positrones / Enfermedad de Alzheimer Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Nucl Med Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas tau / Radiofármacos / Tomografía de Emisión de Positrones / Enfermedad de Alzheimer Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Nucl Med Año: 2018 Tipo del documento: Article