αT-catenin: A developmentally dispensable, disease-linked member of the α-catenin family.
Tissue Barriers
; 6(2): e1463896, 2018.
Article
en En
| MEDLINE
| ID: mdl-29746206
ABSTRACT
α-Catenins are actin-filament binding proteins and critical subunits of the cadherin-catenin cell-cell adhesive complex. They are found in nominally-defined epithelial (E), neural (N), and testis (T) forms transcribed from three distinct genes. While most of α-catenin research has focused on the developmentally essential founding member, αE-catenin, this review discusses recent studies on αT-catenin (CTNNA3), a developmentally dispensable isoform that is emerging as relevant to cardiac, allergic and neurological diseases.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Alfa Catenina
Tipo de estudio:
Etiology_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Tissue Barriers
Año:
2018
Tipo del documento:
Article