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Effective silencing of ENaC by siRNA delivered with epithelial-targeted nanocomplexes in human cystic fibrosis cells and in mouse lung.
Tagalakis, Aristides D; Munye, Mustafa M; Ivanova, Rositsa; Chen, Hanpeng; Smith, Claire M; Aldossary, Ahmad M; Rosa, Luca Z; Moulding, Dale; Barnes, Josephine L; Kafetzis, Konstantinos N; Jones, Stuart A; Baines, Deborah L; Moss, Guy W J; O'Callaghan, Christopher; McAnulty, Robin J; Hart, Stephen L.
Afiliación
  • Tagalakis AD; Experimental and Personalised Medicine Section, UCL Great Ormond Street Institute of Child Health, London, UK.
  • Munye MM; Experimental and Personalised Medicine Section, UCL Great Ormond Street Institute of Child Health, London, UK.
  • Ivanova R; Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK.
  • Chen H; Institute of Pharmaceutical Science, Faculty of Life Science and Medicine, King's College London, London, UK.
  • Smith CM; Respiratory, Critical Care and Anaesthesia, UCL Great Ormond Street Institute of Child Health, London, UK.
  • Aldossary AM; Experimental and Personalised Medicine Section, UCL Great Ormond Street Institute of Child Health, London, UK.
  • Rosa LZ; Experimental and Personalised Medicine Section, UCL Great Ormond Street Institute of Child Health, London, UK.
  • Moulding D; UCL Great Ormond Street Institute of Child Health, London, UK.
  • Barnes JL; UCL Respiratory Centre for Inflammation and Tissue Repair, London, UK.
  • Kafetzis KN; Experimental and Personalised Medicine Section, UCL Great Ormond Street Institute of Child Health, London, UK.
  • Jones SA; Institute of Pharmaceutical Science, Faculty of Life Science and Medicine, King's College London, London, UK.
  • Baines DL; Institute of Infection and Immunity, St George's University of London, London, UK.
  • Moss GWJ; Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK.
  • O'Callaghan C; Respiratory, Critical Care and Anaesthesia, UCL Great Ormond Street Institute of Child Health, London, UK.
  • McAnulty RJ; UCL Respiratory Centre for Inflammation and Tissue Repair, London, UK.
  • Hart SL; Experimental and Personalised Medicine Section, UCL Great Ormond Street Institute of Child Health, London, UK.
Thorax ; 73(9): 847-856, 2018 09.
Article en En | MEDLINE | ID: mdl-29748250
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transfección / Silenciador del Gen / Fibrosis Quística / ARN Interferente Pequeño / Canales Epiteliales de Sodio Límite: Animals / Humans Idioma: En Revista: Thorax Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transfección / Silenciador del Gen / Fibrosis Quística / ARN Interferente Pequeño / Canales Epiteliales de Sodio Límite: Animals / Humans Idioma: En Revista: Thorax Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido