KRAS mutation and epithelial-macrophage interplay in pancreatic neoplastic transformation.

Bishehsari, Faraz; Zhang, Lijuan; Barlass, Usman; Preite, Nailliw Z; Turturro, Sanja; Najor, Matthew S; Shetuni, Brandon B; Zayas, Janet P; Mahdavinia, Mahboobeh; Abukhdeir, Abde M; Keshavarzian, Ali

Bishehsari, Faraz; Zhang, Lijuan; Barlass, Usman; Preite, Nailliw Z; Turturro, Sanja; Najor, Matthew S; Shetuni, Brandon B; Zayas, Janet P; Mahdavinia, Mahboobeh; Abukhdeir, Abde M; Keshavarzian, Ali.

Afiliación

Bishehsari F; Department of Medicine, Division of Gastroenterology, Rush University Medical Center, Chicago, IL.
Zhang L; Department of Medicine, Division of Gastroenterology, Rush University Medical Center, Chicago, IL.
Barlass U; Department of Medicine, Rush University Medical Center, Chicago, IL.
Preite NZ; Department of Medicine, Division of Gastroenterology, Rush University Medical Center, Chicago, IL.
Turturro S; Department of Medicine, Division of Hematology, Oncology, and Cell Therapy, Rush University Medical Center, Chicago, IL.
Najor MS; Department of Medicine, Division of Hematology, Oncology, and Cell Therapy, Rush University Medical Center, Chicago, IL.
Shetuni BB; Northwestern Medicine, Central DuPage Hospital, Winfield, IL.
Zayas JP; Department of Medicine, Rush University Medical Center, Chicago, IL.
Mahdavinia M; Department of Medicine, Division of Allergy-Immunology, Rush University Medical Center, Chicago, IL.
Abukhdeir AM; Department of Medicine, Division of Hematology, Oncology, and Cell Therapy, Rush University Medical Center, Chicago, IL.
Keshavarzian A; Department of Medicine, Division of Gastroenterology, Rush University Medical Center, Chicago, IL.

Int J Cancer ; 143(8): 1994-2007, 2018 10 15.

Article en En | MEDLINE | ID: mdl-29756386

Asunto(s)

Transformación Celular Neoplásica/genética; Células Epiteliales/patología; Macrófagos/patología; Mutación/genética; Neoplasias Pancreáticas/genética; Proteínas Proto-Oncogénicas p21(ras)/genética; Animales; Carcinogénesis/genética; Carcinogénesis/patología; Carcinoma Ductal Pancreático/genética; Carcinoma Ductal Pancreático/patología; Línea Celular Tumoral; Proliferación Celular/genética; Transformación Celular Neoplásica/patología; Células Epiteliales/metabolismo; Femenino; Humanos; Macrófagos/metabolismo; Ratones; Ratones Endogámicos NOD; Ratones SCID; Páncreas/metabolismo; Páncreas/patología; Neoplasias Pancreáticas/patología; Lesiones Precancerosas/genética; Lesiones Precancerosas/patología; Células RAW 264.7; Neoplasias Pancreáticas

Palabras clave

KRAS; PEDF; macrophage; pancreas cancer

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Transformación Celular Neoplásica / Proteínas Proto-Oncogénicas p21(ras) / Células Epiteliales / Macrófagos / Mutación Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Int J Cancer Año: 2018 Tipo del documento: Article País de afiliación: Israel

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