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A single cell high content assay detects mitochondrial dysfunction in iPSC-derived neurons with mutations in SNCA.
Little, Daniel; Luft, Christin; Mosaku, Olukunbi; Lorvellec, Maëlle; Yao, Zhi; Paillusson, Sébastien; Kriston-Vizi, Janos; Gandhi, Sonia; Abramov, Andrey Y; Ketteler, Robin; Devine, Michael J; Gissen, Paul.
Afiliación
  • Little D; MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London, United Kingdom. d.little@ucl.ac.uk.
  • Luft C; MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London, United Kingdom.
  • Mosaku O; MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London, United Kingdom.
  • Lorvellec M; MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London, United Kingdom.
  • Yao Z; Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, Queen Square, London, United Kingdom.
  • Paillusson S; The Francis Crick Institute, 1 Midland Road, King's Cross, London, United Kingdom.
  • Kriston-Vizi J; Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London, United Kingdom.
  • Gandhi S; MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London, United Kingdom.
  • Abramov AY; Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, Queen Square, London, United Kingdom.
  • Ketteler R; The Francis Crick Institute, 1 Midland Road, King's Cross, London, United Kingdom.
  • Devine MJ; Department of Molecular Neuroscience, University College London, Institute of Neurology, Queen Square, London, United Kingdom.
  • Gissen P; MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London, United Kingdom.
Sci Rep ; 8(1): 9033, 2018 06 13.
Article en En | MEDLINE | ID: mdl-29899557
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Alfa-Sinucleína / Células Madre Pluripotentes Inducidas / Análisis de la Célula Individual / Neuronas Dopaminérgicas / Mitocondrias / Mutación Límite: Humans Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Alfa-Sinucleína / Células Madre Pluripotentes Inducidas / Análisis de la Célula Individual / Neuronas Dopaminérgicas / Mitocondrias / Mutación Límite: Humans Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido