Association between dietary fiber intake and risk of ovarian cancer: a meta-analysis of observational studies.
J Int Med Res
; 46(10): 3995-4005, 2018 Oct.
Article
en En
| MEDLINE
| ID: mdl-30141692
ABSTRACT
Objective To evaluate the associations between dietary fiber intake and ovarian cancer risk. Methods A literature survey was conducted by searching the PubMed, Web of Science, and Wanfang Med Online databases up to March 1st, 2018. The effect of dietary fiber intake on ovarian cancer risk was evaluated by calculating relative risks with 95% confidence intervals (95%CI) using Stata 12.0 software. Results A total of 17 articles with 149,177 participants including 7609 ovarian cancer patients were included in this analysis. The summarized relative risk for ovarian cancer in participants with the highest compared with the lowest fiber intake was 0.760 (95%CI=0.702-0.823), with no significant between-study heterogeneity ( I2=12.4%). Subgroup analysis according to study design demonstrated positive associations in both cohort studies and case-control studies. Moreover, the results were consistent among populations from America, Europe, and Asia. No publication bias was found by Egger's test or funnel plots. Conclusion This meta-analysis concluded that a high intake of dietary fiber could significantly reduce the risk of ovarian cancer compared with a low fiber intake.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Neoplasias Ováricas
/
Fibras de la Dieta
Tipo de estudio:
Etiology_studies
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Observational_studies
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Risk_factors_studies
/
Systematic_reviews
Límite:
Female
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Humans
País/Región como asunto:
America do norte
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Asia
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Europa
Idioma:
En
Revista:
J Int Med Res
Año:
2018
Tipo del documento:
Article
País de afiliación:
China