Bifunctional Enzyme SpoT Is Involved in Biofilm Formation of Helicobacter pylori with Multidrug Resistance by Upregulating Efflux Pump Hp1174 (<i>gluP</i>).

Ge, Xiaoran; Cai, Yuying; Chen, Zhenghong; Gao, Sizhe; Geng, Xiwen; Li, Ya; Li, Yan; Jia, Jihui; Sun, Yundong

Bifunctional Enzyme SpoT Is Involved in Biofilm Formation of Helicobacter pylori with Multidrug Resistance by Upregulating Efflux Pump Hp1174 (gluP).

Ge, Xiaoran; Cai, Yuying; Chen, Zhenghong; Gao, Sizhe; Geng, Xiwen; Li, Ya; Li, Yan; Jia, Jihui; Sun, Yundong.

Afiliación

Ge X; Department of Microbiology, Key Laboratory for Experimental Teratology of Ministry of Education, Shandong Provincial Key Laboratory of Infection and Immunology, Shandong University School of Basic Medicine, Jinan, Shandong, People's Republic of China.
Cai Y; Department of Microbiology, Key Laboratory for Experimental Teratology of Ministry of Education, Shandong Provincial Key Laboratory of Infection and Immunology, Shandong University School of Basic Medicine, Jinan, Shandong, People's Republic of China.
Chen Z; Department of Microbiology, Guiyang Medical University, Guiyang, Guizhou, People's Republic of China.
Gao S; Department of Microbiology, Key Laboratory for Experimental Teratology of Ministry of Education, Shandong Provincial Key Laboratory of Infection and Immunology, Shandong University School of Basic Medicine, Jinan, Shandong, People's Republic of China.
Geng X; Department of Microbiology, Key Laboratory for Experimental Teratology of Ministry of Education, Shandong Provincial Key Laboratory of Infection and Immunology, Shandong University School of Basic Medicine, Jinan, Shandong, People's Republic of China.
Li Y; Department of Microbiology, Key Laboratory for Experimental Teratology of Ministry of Education, Shandong Provincial Key Laboratory of Infection and Immunology, Shandong University School of Basic Medicine, Jinan, Shandong, People's Republic of China.
Li Y; School of Control Science and Engineering, Shandong University, Jinan, People's Republic of China.
Jia J; Department of Microbiology, Key Laboratory for Experimental Teratology of Ministry of Education, Shandong Provincial Key Laboratory of Infection and Immunology, Shandong University School of Basic Medicine, Jinan, Shandong, People's Republic of China.
Sun Y; Department of Microbiology, Key Laboratory for Experimental Teratology of Ministry of Education, Shandong Provincial Key Laboratory of Infection and Immunology, Shandong University School of Basic Medicine, Jinan, Shandong, People's Republic of China syd@sdu.edu.cn.

Antimicrob Agents Chemother ; 62(11)2018 11.

Article en En | MEDLINE | ID: mdl-30181372

Asunto(s)

Proteínas Bacterianas/metabolismo; Biopelículas/crecimiento & desarrollo; Farmacorresistencia Bacteriana Múltiple/fisiología; Helicobacter pylori/metabolismo; Regulación hacia Arriba/fisiología; Animales; Antibacterianos/farmacología; Biopelículas/efectos de los fármacos; Farmacorresistencia Bacteriana Múltiple/efectos de los fármacos; Guanosina Pentafosfato/metabolismo; Infecciones por Helicobacter/tratamiento farmacológico; Helicobacter pylori/efectos de los fármacos; Humanos; Pruebas de Sensibilidad Microbiana/métodos; Ovinos; Activación Transcripcional/efectos de los fármacos; Activación Transcripcional/fisiología; Regulación hacia Arriba/efectos de los fármacos

Palabras clave

GluP; Helicobacter pylori; SpoT; antibiotic resistance; biofilm; efflux pump

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Regulación hacia Arriba / Helicobacter pylori / Biopelículas / Farmacorresistencia Bacteriana Múltiple Límite: Animals / Humans Idioma: En Revista: Antimicrob Agents Chemother Año: 2018 Tipo del documento: Article

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