MicroRNA-493 targets STMN-1 and promotes hypoxia-induced epithelial cell cycle arrest in G<sub>2</sub>/M and renal fibrosis.

Liu, Ting; Liu, Limin; Liu, Minna; Du, Rui; Dang, Yangjie; Bai, Ming; Zhang, Lei; Ma, Feng; Yang, Xiaoxia; Ning, Xiaoxuan; Sun, Shiren

MicroRNA-493 targets STMN-1 and promotes hypoxia-induced epithelial cell cycle arrest in G₂/M and renal fibrosis.

Liu, Ting; Liu, Limin; Liu, Minna; Du, Rui; Dang, Yangjie; Bai, Ming; Zhang, Lei; Ma, Feng; Yang, Xiaoxia; Ning, Xiaoxuan; Sun, Shiren.

Afiliación

Liu T; Department of Nephrology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Liu L; State Key Laboratory of Cancer Biology, Fourth Military Medical University, Xi'an, China.
Liu M; Department of Nephrology, Guangren Hospital of Xi'an Jiaotong University, Xi'an, China.
Du R; Department of Nephrology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Dang Y; State Key Laboratory of Cancer Biology, Fourth Military Medical University, Xi'an, China.
Bai M; Department of Nephrology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Zhang L; State Key Laboratory of Cancer Biology, Fourth Military Medical University, Xi'an, China.
Ma F; Department of Radiation Oncology, Navy General Hospital, Beijing, China.
Yang X; Department of Anesthesiology, Children Hospital of Xi'an, Xi'an, China.
Ning X; Department of Nephrology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Sun S; State Key Laboratory of Cancer Biology, Fourth Military Medical University, Xi'an, China.

FASEB J ; 33(2): 1565-1577, 2019 02.

Article en En | MEDLINE | ID: mdl-30183377

Asunto(s)

Puntos de Control del Ciclo Celular/genética; División Celular; Fase G2; Hipoxia/metabolismo; Enfermedades Renales/patología; MicroARNs/genética; Estatmina/genética; Adulto; Animales; Línea Celular; Femenino; Fibrosis/patología; Fibrosis/prevención & control; Humanos; Enfermedades Renales/prevención & control; Túbulos Renales/patología; Masculino; Ratones; Ratones Endogámicos C57BL; Persona de Mediana Edad; Adulto Joven

Palabras clave

HIF-1α; chronic kidney injury; hypoxia; tubular cell

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: División Celular / Fase G2 / MicroARNs / Estatmina / Puntos de Control del Ciclo Celular / Enfermedades Renales / Hipoxia Límite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: China

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