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BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation.
Li, Andrew G; Murphy, Elizabeth C; Culhane, Aedin C; Powell, Emily; Wang, Hua; Bronson, Roderick T; Von, Thanh; Giobbie-Hurder, Anita; Gelman, Rebecca S; Briggs, Kimberly J; Piwnica-Worms, Helen; Zhao, Jean J; Kung, Andrew L; Kaelin, William G; Livingston, David M.
Afiliación
  • Li AG; Department of Genetics, Harvard Medical School, Boston, MA 02115; andrew_li@dfci.harvard.edu david_livingston@dfci.harvard.edu.
  • Murphy EC; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215.
  • Culhane AC; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215.
  • Powell E; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02215.
  • Wang H; Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA 02115.
  • Bronson RT; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Von T; Department of Genetics, Harvard Medical School, Boston, MA 02115.
  • Giobbie-Hurder A; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215.
  • Gelman RS; Department of Pathology, Harvard Medical School, Boston, MA 02115.
  • Briggs KJ; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215.
  • Piwnica-Worms H; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02215.
  • Zhao JJ; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02215.
  • Kung AL; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02215.
  • Kaelin WG; Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA 02115.
  • Livingston DM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215.
Proc Natl Acad Sci U S A ; 115(41): E9600-E9609, 2018 10 09.
Article en En | MEDLINE | ID: mdl-30254159
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Empalme Alternativo / Proteína BRCA1 / Fosfohidrolasa PTEN / Subunidad alfa del Factor 1 Inducible por Hipoxia / Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Empalme Alternativo / Proteína BRCA1 / Fosfohidrolasa PTEN / Subunidad alfa del Factor 1 Inducible por Hipoxia / Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article