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A newly generated neuronal cell model of CLN7 disease reveals aberrant lysosome motility and impaired cell survival.
von Kleist, Lisa; Ariunbat, Khandsuren; Braren, Ingke; Stauber, Tobias; Storch, Stephan; Danyukova, Tatyana.
Afiliación
  • von Kleist L; Institute of Chemistry and Biochemistry, Freie Universität Berlin, 14195 Berlin, Germany. Electronic address: lisa.kleist@fu-berlin.de.
  • Ariunbat K; Section Biochemistry, Children's Hospital, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany. Electronic address: khandsuren.ariunbat@stud.uke.uni-hamburg.de.
  • Braren I; Vector Core Unit, Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany. Electronic address: ibraren@uke.de.
  • Stauber T; Institute of Chemistry and Biochemistry, Freie Universität Berlin, 14195 Berlin, Germany. Electronic address: tobias.stauber@fu-berlin.de.
  • Storch S; Section Biochemistry, Children's Hospital, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany. Electronic address: storch@uke.de.
  • Danyukova T; Section Biochemistry, Children's Hospital, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany. Electronic address: t.danyukova@uke.de.
Mol Genet Metab ; 126(2): 196-205, 2019 02.
Article en En | MEDLINE | ID: mdl-30301600
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas de Transporte de Membrana / Lisosomas / Mutación / Lipofuscinosis Ceroideas Neuronales / Neuronas Límite: Animals Idioma: En Revista: Mol Genet Metab Asunto de la revista: BIOLOGIA MOLECULAR / BIOQUIMICA / METABOLISMO Año: 2019 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas de Transporte de Membrana / Lisosomas / Mutación / Lipofuscinosis Ceroideas Neuronales / Neuronas Límite: Animals Idioma: En Revista: Mol Genet Metab Asunto de la revista: BIOLOGIA MOLECULAR / BIOQUIMICA / METABOLISMO Año: 2019 Tipo del documento: Article