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Discovery and Lead Optimization of Atropisomer D1 Agonists with Reduced Desensitization.
Davoren, Jennifer E; Nason, Deane; Coe, Jotham; Dlugolenski, Keith; Helal, Christopher; Harris, Anthony R; LaChapelle, Erik; Liang, Sidney; Liu, Yue; O'Connor, Rebecca; Orozco, Christine C; Rai, Brajesh K; Salafia, Michelle; Samas, Brian; Xu, Wenjian; Kozak, Rouba; Gray, David.
Afiliación
  • Nason D; Medicine Design , Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States.
  • Coe J; Medicine Design , Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States.
  • Helal C; Medicine Design , Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States.
  • Harris AR; Medicine Design , Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States.
  • LaChapelle E; Medicine Design , Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States.
  • Liang S; Medicine Design , Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States.
  • O'Connor R; Medicine Design , Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States.
  • Orozco CC; Medicine Design , Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States.
  • Salafia M; Medicine Design , Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States.
  • Samas B; Medicine Design , Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States.
  • Xu W; Medicine Design , Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States.
J Med Chem ; 61(24): 11384-11397, 2018 12 27.
Article en En | MEDLINE | ID: mdl-30431269
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores de Dopamina D1 / Agonistas de Dopamina Límite: Animals / Humans / Male Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores de Dopamina D1 / Agonistas de Dopamina Límite: Animals / Humans / Male Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article