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Longitudinal single-cell RNA sequencing of patient-derived primary cells reveals drug-induced infidelity in stem cell hierarchy.
Sharma, Ankur; Cao, Elaine Yiqun; Kumar, Vibhor; Zhang, Xiaoqian; Leong, Hui Sun; Wong, Angeline Mei Lin; Ramakrishnan, Neeraja; Hakimullah, Muhammad; Teo, Hui Min Vivian; Chong, Fui Teen; Chia, Shumei; Thangavelu, Matan Thangavelu; Kwang, Xue Lin; Gupta, Ruta; Clark, Jonathan R; Periyasamy, Giridharan; Iyer, N Gopalakrishna; DasGupta, Ramanuj.
Afiliación
  • Sharma A; Genome Institute of Singapore, Cancer Therapeutics & Stratified Oncology 5, 60 Biopolis Street, #02-01 Genome, Singapore, 138672, Singapore. sharmaa@gis.a-star.edu.sg.
  • Cao EY; Genome Institute of Singapore, Cancer Therapeutics & Stratified Oncology 5, 60 Biopolis Street, #02-01 Genome, Singapore, 138672, Singapore.
  • Kumar V; Genome Institute of Singapore, Cancer Therapeutics & Stratified Oncology 5, 60 Biopolis Street, #02-01 Genome, Singapore, 138672, Singapore.
  • Zhang X; Department of Computational Biology, Indraprastha Institute of Information Technology, Okhla Industrial Estate, Phase III, New Delhi, Delhi, 110020, India.
  • Leong HS; Genome Institute of Singapore, Cancer Therapeutics & Stratified Oncology 5, 60 Biopolis Street, #02-01 Genome, Singapore, 138672, Singapore.
  • Wong AML; National Cancer Centre Singapore, Cancer Therapeutics Research Laboratory, 11 Hospital Drive, 169610, Singapore, Singapore.
  • Ramakrishnan N; Genome Institute of Singapore, Cancer Therapeutics & Stratified Oncology 5, 60 Biopolis Street, #02-01 Genome, Singapore, 138672, Singapore.
  • Hakimullah M; Genome Institute of Singapore, Cancer Therapeutics & Stratified Oncology 5, 60 Biopolis Street, #02-01 Genome, Singapore, 138672, Singapore.
  • Teo HMV; Genome Institute of Singapore, Cancer Therapeutics & Stratified Oncology 5, 60 Biopolis Street, #02-01 Genome, Singapore, 138672, Singapore.
  • Chong FT; Genome Institute of Singapore, Cancer Therapeutics & Stratified Oncology 5, 60 Biopolis Street, #02-01 Genome, Singapore, 138672, Singapore.
  • Chia S; National Cancer Centre Singapore, Cancer Therapeutics Research Laboratory, 11 Hospital Drive, 169610, Singapore, Singapore.
  • Thangavelu MT; Genome Institute of Singapore, Cancer Therapeutics & Stratified Oncology 5, 60 Biopolis Street, #02-01 Genome, Singapore, 138672, Singapore.
  • Kwang XL; Genome Institute of Singapore, Cancer Therapeutics & Stratified Oncology 5, 60 Biopolis Street, #02-01 Genome, Singapore, 138672, Singapore.
  • Gupta R; National Cancer Centre Singapore, Cancer Therapeutics Research Laboratory, 11 Hospital Drive, 169610, Singapore, Singapore.
  • Clark JR; Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital and University of Sydney, Sydney, NSW, 2006, Australia.
  • Periyasamy G; Chris O'Brien Lifehouse and Sydney Head and Neck Cancer Institute, Sydney, NSW, 2050, Australia.
  • Iyer NG; Genome Institute of Singapore, Cancer Therapeutics & Stratified Oncology 5, 60 Biopolis Street, #02-01 Genome, Singapore, 138672, Singapore.
  • DasGupta R; National Cancer Centre Singapore, Cancer Therapeutics Research Laboratory, 11 Hospital Drive, 169610, Singapore, Singapore. gopaliyer@nccs.com.sg.
Nat Commun ; 9(1): 4931, 2018 11 22.
Article en En | MEDLINE | ID: mdl-30467425
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Neoplasias de la Boca / Carcinoma de Células Escamosas / Análisis de Secuencia de ARN / Resistencia a Antineoplásicos / Análisis de la Célula Individual Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2018 Tipo del documento: Article País de afiliación: Singapur
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Neoplasias de la Boca / Carcinoma de Células Escamosas / Análisis de Secuencia de ARN / Resistencia a Antineoplásicos / Análisis de la Célula Individual Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2018 Tipo del documento: Article País de afiliación: Singapur