Cognitive skills in preterm infants with bronchopulmonary dysplasia at 1 year adjusted and 2 years chronological age.
J Matern Fetal Neonatal Med
; 33(13): 2148-2152, 2020 Jul.
Article
en En
| MEDLINE
| ID: mdl-30513032
ABSTRACT
Objective:
The objective of this study was to evaluate for decline in cognitive scores from 12 to 24 months of age for preterm infants ≤32 weeks gestational age for those with and without bronchopulmonary dysplasia.Studydesign:
In an observational retrospective study, detailed medical data was collected from the electronic medical records of preterm infants born between January 2009 and December 2015 who had cognitive evaluations using Bayley Scales of Infant Development, 3rd ed (BISD-3) at 12 months corrected gestational age and 24 months chronological age. Infants were divided into three groups, bronchopulmonary dysplasia (BPD), prolonged oxygen requirement that did not meet BPD criteria, or pulmonary insufficiency (PI), and respiratory distress only (RDS). Decline in cognitive functions was based on the BISD-3 standard deviation of 15 points, no decline ≤3.5 point, moderate, > 3.5 to <7.5 points, significant >7.5 points.Results:
The sample included 165 preterm infants divided into three groups, BPD, n = 39, PI, n = 79, RDS only, n = 47. The groups did not differ on gender, ethnicity, birthweight or gestational age. The groups did not differ in percent of infants who showed no, moderate or significant decline. In all groups, the percentage of infants showing a cognitive decline of >7.5 points varied from 67% to 76%Conclusion:
There was no significant difference in cognitive decline for those with and without BPD. Of note is that a large percentage of infants in each group showed at least one-half standard deviation of cognitive decline across the 12 and 24 months evaluations. Our concern is that correcting for gestational age at 12 months may delay early intervention when significant delays are found at 24 months.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Displasia Broncopulmonar
/
Disfunción Cognitiva
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Child, preschool
/
Female
/
Humans
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Infant
/
Male
Idioma:
En
Revista:
J Matern Fetal Neonatal Med
Asunto de la revista:
OBSTETRICIA
/
PERINATOLOGIA
Año:
2020
Tipo del documento:
Article
País de afiliación:
Estados Unidos