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A simple problem formulation framework to create the right solution to the right problem.
Sauve-Ciencewicki, Alaina; Davis, Kathryn P; McDonald, Justin; Ramanarayanan, Tharacad; Raybould, Alan; Wolf, Douglas C; Valenti, Ted.
Afiliación
  • Sauve-Ciencewicki A; Syngenta Crop Protection, Research Triangle Park, NC, 27709, USA.
  • Davis KP; Syngenta Crop Protection, Research Triangle Park, NC, 27709, USA.
  • McDonald J; Syngenta Crop Protection, Research Triangle Park, NC, 27709, USA.
  • Ramanarayanan T; Syngenta Crop Protection, Greensboro, NC, USA.
  • Raybould A; Syngenta Crop Protection, Basel, Switzerland.
  • Wolf DC; Syngenta Crop Protection, Research Triangle Park, NC, 27709, USA. Electronic address: doug.wolf@syngenta.com.
  • Valenti T; Syngenta Crop Protection, Greensboro, NC, USA.
Regul Toxicol Pharmacol ; 101: 187-193, 2019 Feb.
Article en En | MEDLINE | ID: mdl-30513358
ABSTRACT
A systematic approach to formulate consistent, technically robust and scientifically tractable problems will facilitate achieving innovative and effective solutions in risk evaluation. The fundamentals of problem formulation have been adapted from environmental and human health risk assessments. A structured problem formulation enables focus on describing and evaluating the specifics of the problem to be solved, instead of immediately creating solutions. First the problem should be framed to provide clarity and gain agreement on the problem to be addressed, resulting in a specific problem statement. Second the problem is explored in order to transform it into an operational state through questions to answer, hypotheses to test, and represented by a conceptual model. Finally the approach to testing hypotheses is mapped and the analysis plan is developed to address the problem statement. This simple adaptable framework can be applied to any circumstance to resolve a specific problem and describe a path to resolution.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Solución de Problemas / Proyectos de Investigación Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Regul Toxicol Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Solución de Problemas / Proyectos de Investigación Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Regul Toxicol Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos