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Vectored delivery of anti-SIV envelope targeting mAb via AAV8 protects rhesus macaques from repeated limiting dose intrarectal swarm SIVsmE660 challenge.
Welles, Hugh C; Jennewein, Madeleine F; Mason, Rosemarie D; Narpala, Sandeep; Wang, Lingshu; Cheng, Cheng; Zhang, Yi; Todd, John-Paul; Lifson, Jeffrey D; Balazs, Alejandro B; Alter, Galit; McDermott, Adrian B; Mascola, John R; Roederer, Mario.
Afiliación
  • Welles HC; Immunotechnology Section, Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Jennewein MF; Institute for Biomedical Sciences, The George Washington University, Washington, DC, United States of America.
  • Mason RD; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
  • Narpala S; Immunotechnology Section, Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Wang L; Immunotechnology Section, Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Cheng C; Immunotechnology Section, Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Zhang Y; Immunotechnology Section, Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Todd JP; Immunotechnology Section, Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Lifson JD; Immunotechnology Section, Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Balazs AB; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory of Cancer Research, Frederick, Maryland, United States of America.
  • Alter G; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
  • McDermott AB; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
  • Mascola JR; Immunotechnology Section, Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Roederer M; Immunotechnology Section, Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
PLoS Pathog ; 14(12): e1007395, 2018 12.
Article en En | MEDLINE | ID: mdl-30517201
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Terapia Genética / Proteínas del Envoltorio Viral / Inmunización Pasiva / Vacunas contra el SIDAS / Anticuerpos Antivirales Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: PLoS Pathog Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Terapia Genética / Proteínas del Envoltorio Viral / Inmunización Pasiva / Vacunas contra el SIDAS / Anticuerpos Antivirales Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: PLoS Pathog Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos