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Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study.
Menditto, Enrica; Costa, Elisio; Midão, Luis; Bosnic-Anticevich, Sinthia; Novellino, Ettore; Bialek, Slawomir; Briedis, Vitalis; Mair, Alpana; Rajabian-Soderlund, Rojin; Arnavielhe, Sylvie; Bedbrook, Anna; Czarlewski, Wienczyslawa; Annesi-Maesano, Isabella; Anto, Josep M; Devillier, Philippe; De Vries, Govert; Keil, Thomas; Sheikh, Aziz; Orlando, Valentina; Larenas-Linnemann, Désirée; Cecchi, Lorenzo; De Feo, Giulia; Illario, M; Stellato, Cristiana; Fonseca, Joao; Malva, Joao; Morais-Almeida, Mario; Pereira, Ana Maria; Todo-Bom, Ana Maria; Kvedariene, Violeta; Valiulis, Arunas; Bergmann, Karl Christian; Klimek, Ludger; Mösges, Ralph; Pfaar, Oliver; Zuberbier, Torsten; Cardona, Vicky; Mullol, Joaquim; Papadopoulos, Nikos G; Prokopakis, Emmanuel P; Bewick, Mike; Ryan, Dermot; Roller-Wirnsberger, Regina E; Tomazic, Peter Valentin; Cruz, Alvaro A; Kuna, Piotr; Samolinski, Boleslaw; Fokkens, Wytske J; Reitsma, Sietze; Bosse, Isabelle.
Afiliación
  • Menditto E; CIRFF, Center of Pharmacoeconomics, University of Naples Federico II, Naples, Italy.
  • Costa E; UCIBIO, REQUIMTE, Faculty of Pharmacy, and Competence Center on Active and Healthy Ageing of University of Porto (Porto4Ageing), University of Porto, Porto, Portugal.
  • Midão L; UCIBIO, REQUIMTE, Faculty of Pharmacy, and Competence Center on Active and Healthy Ageing of University of Porto (Porto4Ageing), University of Porto, Porto, Portugal.
  • Bosnic-Anticevich S; Woolcock Institute of Medical Research, University of Sydney Woolcock Emphysema Centre and Sydney Local Health District, Glebe, New South Wales, Australia.
  • Novellino E; University of Naples Federico II, Naples, Italy.
  • Bialek S; Department of Biochemistry and Clinical Chemistry, Faculty of Pharmacy with the Division of Laboratory Medicine, Warsaw Medical University, Warsaw, Poland.
  • Briedis V; Lithuanian University of Health Sciences, Kaunas, Lithuania.
  • Mair A; DG for Health and Social Care, Scottish Government, Edinburgh, UK.
  • Rajabian-Soderlund R; Department of Nephrology and Endocrinology, Karolinska University Hospital, Stockholm, Sweden.
  • Arnavielhe S; KYomed INNOV, Montpellier, France.
  • Bedbrook A; MACVIA-France, Fondation partenariale FMC VIA-LR, Montpellier, France.
  • Czarlewski W; Medical Consulting Czarlewski, Levallois, France.
  • Annesi-Maesano I; Epidemiology of Allergic and Respiratory Diseases, Department Institute Pierre Louis of Epidemiology and Public Health, INSERM and Sorbonne Université, Medical School Saint Antoine, Paris, France.
  • Anto JM; ISGlobAL, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain.
  • Devillier P; IMIM (Hospital del Mar Research Institute), Barcelona, Spain.
  • De Vries G; CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain.
  • Keil T; Universitat Pompeu Fabra (UPF), Barcelona, Spain.
  • Sheikh A; Laboratoire de Pharmacologie Respiratoire UPRES EA220, Hôpital Foch, Suresnes, France.
  • Orlando V; Université Versailles Saint-Quentin, Université Paris Saclay, Paris Saclay, France.
  • Larenas-Linnemann D; Peercode BV, Geldermalsen, The Netherlands.
  • Cecchi L; Institute of Social Medicine, Epidemiology and Health Economics, Charité - Universitätsmedizin Berlin, Berlin, Germany.
  • De Feo G; Institute for Clinical Epidemiology and Biometry, University of Wuerzburg, Wuerzburg, Germany.
  • Illario M; The Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, UK.
  • Stellato C; CIRFF, Center of Pharmacoeconomics, University of Naples Federico II, Naples, Italy.
  • Fonseca J; Center of Excellence in Asthma and Allergy, Médica Sur Clinical Foundation and Hospital, México City, Mexico.
  • Malva J; SOS Allergology and Clinical Immunology, USL Toscana Centro, Prato, Italy.
  • Morais-Almeida M; Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Salerno, Italy.
  • Pereira AM; Division for Health Innovation, Campania Region and Federico II University Hospital Naples (R&D and DISMET), Naples, Italy.
  • Todo-Bom AM; Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Salerno, Italy.
  • Kvedariene V; CINTESIS, Center for Research in Health Technologies and Information Systems, Faculdade de Medicina da Universidade do Porto, Porto, Portugal.
  • Valiulis A; MEDIDA, Lda, Porto, Portugal.
  • Bergmann KC; Faculty of Medicine, Coimbra Institute for Clinical and Biomedical Research (iCBR), University of Coimbra, Coimbra, Portugal.
  • Klimek L; Ageing@Coimbra EIP-AHA Reference Site, Coimbra, Portugal.
  • Mösges R; Allergy Center, CUF Descobertas Hospital, Lisbon, Portugal.
  • Pfaar O; Allergy Unit, CUF-Porto Hospital and Institute, Porto, Portugal.
  • Zuberbier T; Center for Research in Health Technologies and Information Systems CINTESIS, Universidade do Porto, Porto, Portugal.
  • Cardona V; Imunoalergologia, Centro Hospitalar Universitário de Coimbra and Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
  • Mullol J; Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
  • Papadopoulos NG; Department of Public Health, Clinic of Children's Diseases, and Institute of Health Sciences, Vilnius University Institute of Clinical Medicine, Vilnius, Lithuania.
  • Prokopakis EP; European Academy of Paediatrics (EAP/UEMS-SP), Brussels, Belgium.
  • Bewick M; Charité - Universitätsmedizin Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
  • Ryan D; Department of Dermatology and Allergy, Comprehensive Allergy Center, Berlin Institute of Health, Berlin, Germany.
  • Roller-Wirnsberger RE; Euforea, Brussels, Belgium.
  • Tomazic PV; Medical Faculty, Institute of Medical Statistics, and Computational Biology, University of Cologne, Cologne, Germany.
  • Cruz AA; CRI-Clinical Research International-Ltd, Hamburg, Germany.
  • Kuna P; Department of Otorhinolaryngology, Head and Neck Surgery, Section of Rhinology and Allergy, University Hospital Marburg, Phillipps-Universität Marburg, Germany.
  • Samolinski B; Charité - Universitätsmedizin Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
  • Fokkens WJ; Department of Dermatology and Allergy, Comprehensive Allergy Center, Berlin Institute of Health, Berlin, Germany.
  • Reitsma S; Allergy Section, Department of Internal Medicine, Hospital Vall d'Hebron, & ARADyAL Spanish Research Network, Barcelona, Spain.
  • Bosse I; Rhinology Unit & Smell Clinic, ENT Department, Hospital Clínic, Barcelona, Spain.
Clin Exp Allergy ; 49(4): 442-460, 2019 04.
Article en En | MEDLINE | ID: mdl-30597673
ABSTRACT

BACKGROUND:

Mobile technology may help to better understand the adherence to treatment. MASK-rhinitis (Mobile Airways Sentinel NetworK for allergic rhinitis) is a patient-centred ICT system. A mobile phone app (the Allergy Diary) central to MASK is available in 22 countries.

OBJECTIVES:

To assess the adherence to treatment in allergic rhinitis patients using the Allergy Diary App.

METHODS:

An observational cross-sectional study was carried out on all users who filled in the Allergy Diary from 1 January 2016 to 1 August 2017. Secondary adherence was assessed by using the modified Medication Possession Ratio (MPR) and the Proportion of days covered (PDC) approach.

RESULTS:

A total of 12 143 users were registered. A total of 6 949 users reported at least one VAS data recording. Among them, 1 887 users reported ≥7 VAS data. About 1 195 subjects were included in the analysis of adherence. One hundred and thirty-six (11.28%) users were adherent (MPR ≥70% and PDC ≤1.25), 51 (4.23%) were partly adherent (MPR ≥70% and PDC = 1.50) and 176 (14.60%) were switchers. On the other hand, 832 (69.05%) users were non-adherent to medications (MPR <70%). Of those, the largest group was non-adherent to medications and the time interval was increased in 442 (36.68%) users. CONCLUSION AND CLINICAL RELEVANCE Adherence to treatment is low. The relative efficacy of continuous vs on-demand treatment for allergic rhinitis symptoms is still a matter of debate. This study shows an approach for measuring retrospective adherence based on a mobile app. This also represents a novel approach for analysing medication-taking behaviour in a real-world setting.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Cumplimiento de la Medicación / Aplicaciones Móviles / Rinitis Alérgica / Uso del Teléfono Celular Tipo de estudio: Clinical_trials / Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Exp Allergy Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Italia
Texto completo
Imprimir
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PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Cumplimiento de la Medicación / Aplicaciones Móviles / Rinitis Alérgica / Uso del Teléfono Celular Tipo de estudio: Clinical_trials / Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Exp Allergy Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Italia