Pancreatic ß-cells detoxify H<sub>2</sub>O<sub>2</sub> through the peroxiredoxin/thioredoxin antioxidant system.

Stancill, Jennifer S; Broniowska, Katarzyna A; Oleson, Bryndon J; Naatz, Aaron; Corbett, John A

Pancreatic ß-cells detoxify H₂O₂ through the peroxiredoxin/thioredoxin antioxidant system.

Stancill, Jennifer S; Broniowska, Katarzyna A; Oleson, Bryndon J; Naatz, Aaron; Corbett, John A.

Afiliación

Stancill JS; From the Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226.
Broniowska KA; From the Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226.
Oleson BJ; From the Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226.
Naatz A; From the Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226.
Corbett JA; From the Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226 jcorbett@mcw.edu.

J Biol Chem ; 294(13): 4843-4853, 2019 03 29.

Article en En | MEDLINE | ID: mdl-30659092

Asunto(s)

Peróxido de Hidrógeno/metabolismo; Células Secretoras de Insulina/metabolismo; Peroxirredoxinas/metabolismo; Tiorredoxinas/metabolismo; Animales; Supervivencia Celular; Daño del ADN; Secreción de Insulina; Masculino; Oxidación-Reducción; Ratas; Ratas Sprague-Dawley; Reductasa de Tiorredoxina-Disulfuro/metabolismo

Palabras clave

ROS detoxification; diabetes; hydrogen peroxide; metabolic dysfunction; oxidative phosphorylation; oxidative stress; reactive oxygen species (ROS); thioredoxin reductase; ß-cell

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tiorredoxinas / Células Secretoras de Insulina / Peroxirredoxinas / Peróxido de Hidrógeno Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Biol Chem Año: 2019 Tipo del documento: Article

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