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Deregulated Gab2 phosphorylation mediates aberrant AKT and STAT3 signaling upon PIK3R1 loss in ovarian cancer.
Li, Xinran; Mak, Victor C Y; Zhou, Yuan; Wang, Chao; Wong, Esther S Y; Sharma, Rakesh; Lu, Yiling; Cheung, Annie N Y; Mills, Gordon B; Cheung, Lydia W T.
Afiliación
  • Li X; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong.
  • Mak VCY; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong.
  • Zhou Y; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong.
  • Wang C; Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.
  • Wong ESY; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong.
  • Sharma R; Proteomics & Metabolomics Core Facility, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong.
  • Lu Y; Department of Systems Biology, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Cheung ANY; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong.
  • Mills GB; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, 97239, USA.
  • Cheung LWT; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong. lydiacwt@hku.hk.
Nat Commun ; 10(1): 716, 2019 02 12.
Article en En | MEDLINE | ID: mdl-30755611
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Fosfatidilinositol 3-Quinasas / Proteínas Adaptadoras Transductoras de Señales / Proteínas Proto-Oncogénicas c-akt / Factor de Transcripción STAT3 Límite: Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: Hong Kong
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Fosfatidilinositol 3-Quinasas / Proteínas Adaptadoras Transductoras de Señales / Proteínas Proto-Oncogénicas c-akt / Factor de Transcripción STAT3 Límite: Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: Hong Kong