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Ultrastructural analysis of the Krebs-2 ascites cancer cells treated with extracellular double-stranded DNA preparation.
Kirikovich, Svetlana S; Taranov, Oleg S; Omigov, Vladimir V; Potter, Ekaterina A; Dolgova, Evgenia V; Proskurina, Anastasia S; Efremov, Yaroslav R; Bogachev, Sergey S.
Afiliación
  • Kirikovich SS; a Institute of Cytology and Genetics , Siberian Branch of the Russian Academy of Sciences , Novosibirsk , Russia.
  • Taranov OS; b State Research Center of Virology and Biotechnology VECTOR , Rospotrebnadzor , Novosibirsk region , Russia.
  • Omigov VV; b State Research Center of Virology and Biotechnology VECTOR , Rospotrebnadzor , Novosibirsk region , Russia.
  • Potter EA; a Institute of Cytology and Genetics , Siberian Branch of the Russian Academy of Sciences , Novosibirsk , Russia.
  • Dolgova EV; a Institute of Cytology and Genetics , Siberian Branch of the Russian Academy of Sciences , Novosibirsk , Russia.
  • Proskurina AS; a Institute of Cytology and Genetics , Siberian Branch of the Russian Academy of Sciences , Novosibirsk , Russia.
  • Efremov YR; a Institute of Cytology and Genetics , Siberian Branch of the Russian Academy of Sciences , Novosibirsk , Russia.
  • Bogachev SS; c Department of natural sciences , Novosibirsk State University , Novosibirsk , Russia.
Ultrastruct Pathol ; 43(1): 56-65, 2019.
Article en En | MEDLINE | ID: mdl-30758240
ABSTRACT
Electron-microscopic analysis of the ultrastructure of the Krebs-2 carcinoma ascites cells in the first 90 min immediately after their exposure to fragmented double-stranded DNA has been performed. Morphological attributes of the treated cancer cells indicate the induction in these cells of destructive processes of presumably apoptotic type. The predominance of dystrophic-destructive changes in cells after the addition of DNA is supposed to be a consequence of the disturbance in metabolic processes caused by the experimental action.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: ADN / Carcinoma Krebs 2 / Membrana Celular / Citoplasma Límite: Animals Idioma: En Revista: Ultrastruct Pathol Año: 2019 Tipo del documento: Article País de afiliación: Rusia

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: ADN / Carcinoma Krebs 2 / Membrana Celular / Citoplasma Límite: Animals Idioma: En Revista: Ultrastruct Pathol Año: 2019 Tipo del documento: Article País de afiliación: Rusia