A Bayesian model-free approach to combination therapy phase I trials using censored time-to-toxicity data.

Wheeler, Graham M; Sweeting, Michael J; Mander, Adrian P

Wheeler, Graham M; Sweeting, Michael J; Mander, Adrian P.

Afiliación

Wheeler GM; Cancer Research UK and UCL Cancer Trials Centre, University College London, UK.
Sweeting MJ; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, UK; Department of Health Sciences, University of Leicester, UK.
Mander AP; MRC Biostatistics Unit Hub for Trials Methodology Research, University of Cambridge, UK.

J R Stat Soc Ser C Appl Stat ; 68(2): 309-329, 2019 Feb.

Article en En | MEDLINE | ID: mdl-30880843

Palabras clave

Adaptive designs; Bayesian methods; Clinical trials; Dose escalation; Model-free; Time-to-event

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: J R Stat Soc Ser C Appl Stat Año: 2019 Tipo del documento: Article País de afiliación: Reino Unido

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