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Quantitative Contribution of Six Major Transporters to the Hepatic Uptake of Drugs: "SLC-Phenotyping" Using Primary Human Hepatocytes.
Bi, Yi-An; Costales, Chester; Mathialagan, Sumathy; West, Mark; Eatemadpour, Soraya; Lazzaro, Sarah; Tylaska, Laurie; Scialis, Renato; Zhang, Hui; Umland, John; Kimoto, Emi; Tess, David A; Feng, Bo; Tremaine, Larry M; Varma, Manthena V S; Rodrigues, A David.
Afiliación
  • Bi YA; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Costales C; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Mathialagan S; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • West M; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Eatemadpour S; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Lazzaro S; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Tylaska L; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Scialis R; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Zhang H; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Umland J; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Kimoto E; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Tess DA; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Feng B; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Tremaine LM; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Varma MVS; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut manthena.v.varma@pfizer.com.
  • Rodrigues AD; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
J Pharmacol Exp Ther ; 370(1): 72-83, 2019 07.
Article en En | MEDLINE | ID: mdl-30975793
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fenotipo / Preparaciones Farmacéuticas / Hepatocitos / Proteínas Transportadoras de Solutos / Hígado Límite: Humans Idioma: En Revista: J Pharmacol Exp Ther Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fenotipo / Preparaciones Farmacéuticas / Hepatocitos / Proteínas Transportadoras de Solutos / Hígado Límite: Humans Idioma: En Revista: J Pharmacol Exp Ther Año: 2019 Tipo del documento: Article