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Somatic variants in epigenetic modifiers can predict failure of response to imatinib but not to second-generation tyrosine kinase inhibitors.
Nteliopoulos, Georgios; Bazeos, Alexandra; Claudiani, Simone; Gerrard, Gareth; Curry, Edward; Szydlo, Richard; Alikian, Mary; Foong, Hui En; Nikolakopoulou, Zacharoula; Loaiza, Sandra; Khorashad, Jamshid S; Milojkovic, Dragana; Perrotti, Danilo; Gale, Robert Peter; Foroni, Letizia; Apperley, Jane F.
Afiliación
  • Nteliopoulos G; Centre for Haematology, Department of Medicine, Imperial College, London, UK georgios.nteliopoulos04@imperial.ac.uk.
  • Bazeos A; Centre for Haematology, Department of Medicine, Imperial College, London, UK.
  • Claudiani S; Centre for Haematology, Department of Medicine, Imperial College, London, UK.
  • Gerrard G; Imperial College Healthcare NHS Trust, London, UK.
  • Curry E; Centre for Haematology, Department of Medicine, Imperial College, London, UK.
  • Szydlo R; Sarah Cannon Molecular Diagnostics, HCA Healthcare UK, London, UK.
  • Alikian M; Department of Surgery and Cancer, Ovarian Cancer Action Research Centre, Imperial College, London, UK.
  • Foong HE; Centre for Haematology, Department of Medicine, Imperial College, London, UK.
  • Nikolakopoulou Z; Centre for Haematology, Department of Medicine, Imperial College, London, UK.
  • Loaiza S; Imperial College Healthcare NHS Trust, London, UK.
  • Khorashad JS; Imperial College Healthcare NHS Trust, London, UK.
  • Milojkovic D; Centre for Haematology, Department of Medicine, Imperial College, London, UK.
  • Perrotti D; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK.
  • Gale RP; Centre for Haematology, Department of Medicine, Imperial College, London, UK.
  • Foroni L; Imperial College Healthcare NHS Trust, London, UK.
  • Apperley JF; Centre for Haematology, Department of Medicine, Imperial College, London, UK.
Haematologica ; 104(12): 2400-2409, 2019 12.
Article en En | MEDLINE | ID: mdl-31073075
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Leucemia Mielógena Crónica BCR-ABL Positiva / Biomarcadores de Tumor / Regulación Neoplásica de la Expresión Génica / Epigénesis Genética / Inhibidores de Proteínas Quinasas / Mesilato de Imatinib / Mutación Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Haematologica Año: 2019 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Leucemia Mielógena Crónica BCR-ABL Positiva / Biomarcadores de Tumor / Regulación Neoplásica de la Expresión Génica / Epigénesis Genética / Inhibidores de Proteínas Quinasas / Mesilato de Imatinib / Mutación Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Haematologica Año: 2019 Tipo del documento: Article País de afiliación: Reino Unido